node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69978.1 | pdxS | MSMEG_2940 | MSMEG_2937 | Conserved hypothetical protein; Identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.841 |
ABK69978.1 | pdxT | MSMEG_2940 | MSMEG_2939 | Conserved hypothetical protein; Identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033. | Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.842 |
ABK69978.1 | tesB | MSMEG_2940 | MSMEG_2938 | Conserved hypothetical protein; Identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033. | acyl-CoA thioesterase II; Identified by match to protein family HMM PF02551; match to protein family HMM TIGR00189. | 0.750 |
ABK72539.1 | derI1 | MSMEG_2165 | MSMEG_3272 | Transketolase, N- subunit; Identified by match to protein family HMM PF00456. | Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of erythritol and D- threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family. | 0.931 |
ABK72539.1 | pdxS | MSMEG_2165 | MSMEG_2937 | Transketolase, N- subunit; Identified by match to protein family HMM PF00456. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.815 |
ABK72539.1 | pdxT | MSMEG_2165 | MSMEG_2939 | Transketolase, N- subunit; Identified by match to protein family HMM PF00456. | Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.804 |
ABK72539.1 | rbsK | MSMEG_2165 | MSMEG_4585 | Transketolase, N- subunit; Identified by match to protein family HMM PF00456. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.910 |
ABK72539.1 | tal | MSMEG_2165 | MSMEG_3102 | Transketolase, N- subunit; Identified by match to protein family HMM PF00456. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.932 |
ABK72539.1 | tal-2 | MSMEG_2165 | MSMEG_4415 | Transketolase, N- subunit; Identified by match to protein family HMM PF00456. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.931 |
ABK73057.1 | pdxH | MSMEG_0464 | MSMEG_5675 | Phosphomethylpyrimidine kinase. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.913 |
ABK73057.1 | pdxS | MSMEG_0464 | MSMEG_2937 | Phosphomethylpyrimidine kinase. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.920 |
ABK73057.1 | pdxT | MSMEG_0464 | MSMEG_2939 | Phosphomethylpyrimidine kinase. | Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.918 |
derI1 | ABK72539.1 | MSMEG_3272 | MSMEG_2165 | Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of erythritol and D- threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family. | Transketolase, N- subunit; Identified by match to protein family HMM PF00456. | 0.931 |
derI1 | pdxS | MSMEG_3272 | MSMEG_2937 | Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of erythritol and D- threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.807 |
derI1 | pdxT | MSMEG_3272 | MSMEG_2939 | Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of erythritol and D- threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family. | Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.804 |
derI1 | rbsK | MSMEG_3272 | MSMEG_4585 | Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of erythritol and D- threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.915 |
derI1 | tal | MSMEG_3272 | MSMEG_3102 | Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of erythritol and D- threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.407 |
derI1 | tal-2 | MSMEG_3272 | MSMEG_4415 | Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of erythritol and D- threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.413 |
pdxH | ABK73057.1 | MSMEG_5675 | MSMEG_0464 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Phosphomethylpyrimidine kinase. | 0.913 |
pdxH | pdxS | MSMEG_5675 | MSMEG_2937 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.954 |