STRINGSTRING
priA priA fmt fmt ABK70263.1 ABK70263.1 ABK76147.1 ABK76147.1 ssb ssb smc smc sun sun ABK75351.1 ABK75351.1 ABK70887.1 ABK70887.1 whiA whiA coaBC coaBC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (666 aa)    
Predicted Functional Partners:
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    0.898
ABK70263.1
Conserved hypothetical protein; Identified by match to protein family HMM PF07947.
  
    0.896
ABK76147.1
DNA translocase FtsK; Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family.
 
   
 0.849
ssb
Single-stranded DNA-binding protein; Identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621.
 
 
 
 0.834
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
  
 0.829
sun
Ribosomal RNA small subunit methyltransferase B; Identified by match to protein family HMM PF01029; match to protein family HMM PF01189; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
    0.805
ABK75351.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 
 
 0.767
ABK70887.1
Single-strand binding protein; Identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621.
   
 
 0.754
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
 
     0.739
coaBC
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
  
    0.690
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.