STRINGSTRING
lprG lprG ABK73093.1 ABK73093.1 lspA lspA ribE ribE snm snm ABK73081.1 ABK73081.1 ABK70069.1 ABK70069.1 ABK73297.1 ABK73297.1 ABK72671.1 ABK72671.1 ABK70716.1 ABK70716.1 ABK74803.1 ABK74803.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
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Textmining
[Homology]
Score
lprGLprG protein; Probably helps membrane protein MSMEG_3069/MSMEI_2992 (P55) transport triacylglycerides (TAG) across the inner cell membrane into the periplasm and probably ultimately to the outer membrane (By similarity). Required for MSMEG_3069/MSMEI_2992 export activity. Export of ethidium bromide by MSMEG_3069/MSMEI_2992 can be complemented by the equivalent operon from M.tuberculosis (lprG-Rv1410c). Belongs to the LppX/LprAFG lipoprotein family. (236 aa)    
Predicted Functional Partners:
ABK73093.1
Aminoglycosides/tetracycline-transport integral membrane protein; In association with lipoprotein LprG probably transports triacyglycerides (TAG) across the inner cell membrane into the periplasm; TAG probably regulates lipid metabolism and growth regulation (By similarity). Confers resistance to ethidium bromide, possibly acting as an efflux pump, requires LprG lipoprotein for normal function. Export of ethidium bromide can be complemented by the equivalent operon from M.tuberculosis (lprG- Rv1410c) ; Belongs to the major facilitator superfamily.
 
  
 0.986
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
   
  
 0.753
ribE
Riboflavin synthase, alpha subunit; Identified by match to protein family HMM PF00677; match to protein family HMM TIGR00187.
  
  
 0.751
snm
Secretion protein Snm4; Part of the ESX-3 specialized secretion system, which is required for siderophore-mediated iron acquisition and for the secretion of EsxH and EsxG; Belongs to the EccD/Snm4 family.
  
    0.700
ABK73081.1
Antigen 34 kDa.
  
    0.689
ABK70069.1
Conserved hypothetical protein.
  
     0.683
ABK73297.1
Conserved hypothetical protein.
  
    0.597
ABK72671.1
Conserved hypothetical protein.
  
    0.593
ABK70716.1
Identified by match to protein family HMM PF01476.
  
    0.588
ABK74803.1
Alpha-mannosidase; Identified by match to protein family HMM PF01074; match to protein family HMM PF07748.
  
   
 0.575
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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