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ribE ribE ribBA ribBA ribE-2 ribE-2 ribD ribD ribH ribH ABK73093.1 ABK73093.1 ribF ribF ABK73277.1 ABK73277.1 ABK75968.1 ABK75968.1 ABK72801.1 ABK72801.1 ABK74534.1 ABK74534.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ribERiboflavin synthase, alpha subunit; Identified by match to protein family HMM PF00677; match to protein family HMM TIGR00187. (199 aa)    
Predicted Functional Partners:
ribBA
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 
 0.999
ribE-2
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.998
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 0.997
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.996
ABK73093.1
Aminoglycosides/tetracycline-transport integral membrane protein; In association with lipoprotein LprG probably transports triacyglycerides (TAG) across the inner cell membrane into the periplasm; TAG probably regulates lipid metabolism and growth regulation (By similarity). Confers resistance to ethidium bromide, possibly acting as an efflux pump, requires LprG lipoprotein for normal function. Export of ethidium bromide can be complemented by the equivalent operon from M.tuberculosis (lprG- Rv1410c) ; Belongs to the major facilitator superfamily.
  
  
 0.962
ribF
Riboflavin biosynthesis protein RibF; Identified by match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; match to protein family HMM TIGR00125; Belongs to the ribF family.
 
 
 0.945
ABK73277.1
Identified by similarity to GB:AAK38651.1; match to protein family HMM PF00583.
  
  
 0.828
ABK75968.1
Hypothetical protein; Identified by Glimmer2; putative.
   
  
 0.816
ABK72801.1
GTP cyclohydrolase.
 
 
 0.816
ABK74534.1
Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872.
 
  
 0.789
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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