moxR protein (Mycolicibacterium smegmatis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

moxR

Identified by match to protein family HMM PF07726; match to protein family HMM PF07728. (348 aa)

Predicted Functional Partners:

ABK72529.1

0.985

ABK70345.1

0.968

ABK74689.1

0.833

ABK73991.1

0.772

hemH

0.624

ABK72979.1

0.605

ABK72305.1

0.524

ABK70868.1

0.521

inhA

0.482

fabG-3

0.476

Your Current Organism:

Mycolicibacterium smegmatis

NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK70345.1	ABK72529.1	MSMEG_3149	MSMEG_3148	Conserved hypothetical protein; Identified by match to protein family HMM PF00092.	Conserved hypothetical protein.	0.985
ABK70345.1	ABK74689.1	MSMEG_3149	MSMEG_6610	Conserved hypothetical protein; Identified by match to protein family HMM PF00092.	Protein of unknown function DUF58, putative.	0.833
ABK70345.1	fabG-3	MSMEG_3149	MSMEG_3150	Conserved hypothetical protein; Identified by match to protein family HMM PF00092.	3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.564
ABK70345.1	hemH	MSMEG_3149	MSMEG_3152	Conserved hypothetical protein; Identified by match to protein family HMM PF00092.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.	0.612
ABK70345.1	inhA	MSMEG_3149	MSMEG_3151	Conserved hypothetical protein; Identified by match to protein family HMM PF00092.	[NADH] enoyl-[acyl-carrier-protein] reductase; Enoyl-ACP reductase of the type II fatty acid syntase (FAS- II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the double bond of 2-trans- enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway. Shows preference for long-chain fatty acyl thioester substrates (>C16), and can also use 2-trans-enoyl-CoAs as alternative substrates (By similarity). The mycobacterial FAS-II system utilizes th [...]	0.563
ABK70345.1	moxR	MSMEG_3149	MSMEG_3147	Conserved hypothetical protein; Identified by match to protein family HMM PF00092.	Identified by match to protein family HMM PF07726; match to protein family HMM PF07728.	0.968
ABK70868.1	moxR	MSMEG_6220	MSMEG_3147	Lipoprotein; Identified by match to protein family HMM PF01882.	Identified by match to protein family HMM PF07726; match to protein family HMM PF07728.	0.521
ABK72305.1	ABK72979.1	MSMEG_6575	MSMEG_3121	Beta-lactamase; Identified by match to protein family HMM PF00144.	Identified by match to protein family HMM PF01022.	0.815
ABK72305.1	moxR	MSMEG_6575	MSMEG_3147	Beta-lactamase; Identified by match to protein family HMM PF00144.	Identified by match to protein family HMM PF07726; match to protein family HMM PF07728.	0.524
ABK72529.1	ABK70345.1	MSMEG_3148	MSMEG_3149	Conserved hypothetical protein.	Conserved hypothetical protein; Identified by match to protein family HMM PF00092.	0.985
ABK72529.1	fabG-3	MSMEG_3148	MSMEG_3150	Conserved hypothetical protein.	3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.466
ABK72529.1	hemH	MSMEG_3148	MSMEG_3152	Conserved hypothetical protein.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.	0.496
ABK72529.1	inhA	MSMEG_3148	MSMEG_3151	Conserved hypothetical protein.	[NADH] enoyl-[acyl-carrier-protein] reductase; Enoyl-ACP reductase of the type II fatty acid syntase (FAS- II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the double bond of 2-trans- enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway. Shows preference for long-chain fatty acyl thioester substrates (>C16), and can also use 2-trans-enoyl-CoAs as alternative substrates (By similarity). The mycobacterial FAS-II system utilizes th [...]	0.495
ABK72529.1	moxR	MSMEG_3148	MSMEG_3147	Conserved hypothetical protein.	Identified by match to protein family HMM PF07726; match to protein family HMM PF07728.	0.985
ABK72979.1	ABK72305.1	MSMEG_3121	MSMEG_6575	Identified by match to protein family HMM PF01022.	Beta-lactamase; Identified by match to protein family HMM PF00144.	0.815
ABK72979.1	moxR	MSMEG_3121	MSMEG_3147	Identified by match to protein family HMM PF01022.	Identified by match to protein family HMM PF07726; match to protein family HMM PF07728.	0.605
ABK73991.1	moxR	MSMEG_4582	MSMEG_3147	Conserved hypothetical protein; Identified by match to protein family HMM PF05762.	Identified by match to protein family HMM PF07726; match to protein family HMM PF07728.	0.772
ABK74689.1	ABK70345.1	MSMEG_6610	MSMEG_3149	Protein of unknown function DUF58, putative.	Conserved hypothetical protein; Identified by match to protein family HMM PF00092.	0.833
ABK74689.1	moxR	MSMEG_6610	MSMEG_3147	Protein of unknown function DUF58, putative.	Identified by match to protein family HMM PF07726; match to protein family HMM PF07728.	0.833
fabG-3	ABK70345.1	MSMEG_3150	MSMEG_3149	3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Conserved hypothetical protein; Identified by match to protein family HMM PF00092.	0.564