STRINGSTRING
ABK70275.1 ABK70275.1 ftsH ftsH ABK71936.1 ABK71936.1 ABK74866.1 ABK74866.1 ABK72764.1 ABK72764.1 saeC saeC ABK74179.1 ABK74179.1 ABK70031.1 ABK70031.1 ABK75335.1 ABK75335.1 ctpE ctpE mpa mpa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ABK70275.1Band 7 protein; Identified by match to protein family HMM PF01145. (408 aa)    
Predicted Functional Partners:
ftsH
Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.949
ABK71936.1
Membrane protein implicated in regulation of membrane protease activity; Identified by match to protein family HMM PF01957.
 
  
 0.941
ABK74866.1
Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family.
  
 0.783
ABK72764.1
Spfh domain/band 7 family protein, putative; Identified by match to protein family HMM PF01145.
  
 
 0.756
saeC
Conserved hypothetical protein; May be involved in assembly of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Involved in DNA conjugation in recipient (MKD8) strain.
   
 0.746
ABK74179.1
Identified by match to protein family HMM PF01694.
  
 0.718
ABK70031.1
Identified by match to protein family HMM PF01694.
  
 0.716
ABK75335.1
Conserved hypothetical protein.
  
    0.708
ctpE
P-type ATPase - metal cation transport; P-type ATPase involved in specific uptake of calcium. Essential for growth and maintenance of cell surface integrity under Ca(2+)-deficient conditions.
 
 0.675
mpa
ATPase, AAA family protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 
 0.666
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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