Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABK70918.1 | ABK75344.1 | MSMEG_4925 | MSMEG_6275 | Transcriptional regulator, Ada family protein/DNA-3-methyladenine glycosylase II; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | DNA polymerase III subunit epsilon; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | 0.685 |
| ABK70918.1 | dinB-3 | MSMEG_4925 | MSMEG_3172 | Transcriptional regulator, Ada family protein/DNA-3-methyladenine glycosylase II; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.848 |
| ABK70918.1 | lexA | MSMEG_4925 | MSMEG_2740 | Transcriptional regulator, Ada family protein/DNA-3-methyladenine glycosylase II; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.431 |
| ABK70918.1 | ligD-2 | MSMEG_4925 | MSMEG_5570 | Transcriptional regulator, Ada family protein/DNA-3-methyladenine glycosylase II; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | DNA ligase; With Ku forms a non-homologous end joining (NHEJ) repair enzyme which repairs blunt-end and 5'-overhang DNA double strand breaks (DSB) with about 50% fidelity, and DSB with non-complementary 3' ends. Plays a partial role in NHEJ during 3'-overhang repair. NHEJ repairs DSB with blunt ends and 5' overhangs with a high level of nucleotide insertion/deletion, without a need for microhomology. Acts as a DNA ligase on singly nicked dsDNA, as a DNA-directed DNA polymerase on 5' overhangs, and adds non-templated nucleotides to 3' overhangs (terminal transferase). Fills in gaps in d [...] | 0.405 |
| ABK70918.1 | polA | MSMEG_4925 | MSMEG_3839 | Transcriptional regulator, Ada family protein/DNA-3-methyladenine glycosylase II; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.833 |
| ABK70918.1 | recA | MSMEG_4925 | MSMEG_2723 | Transcriptional regulator, Ada family protein/DNA-3-methyladenine glycosylase II; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...] | 0.720 |
| ABK75344.1 | ABK70918.1 | MSMEG_6275 | MSMEG_4925 | DNA polymerase III subunit epsilon; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | Transcriptional regulator, Ada family protein/DNA-3-methyladenine glycosylase II; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | 0.685 |
| ABK75344.1 | dinB-3 | MSMEG_6275 | MSMEG_3172 | DNA polymerase III subunit epsilon; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.716 |
| ABK75344.1 | dnaE2 | MSMEG_6275 | MSMEG_1633 | DNA polymerase III subunit epsilon; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.782 |
| ABK75344.1 | dnaN | MSMEG_6275 | MSMEG_0001 | DNA polymerase III subunit epsilon; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.991 |
| ABK75344.1 | lexA | MSMEG_6275 | MSMEG_2740 | DNA polymerase III subunit epsilon; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.701 |
| ABK75344.1 | polA | MSMEG_6275 | MSMEG_3839 | DNA polymerase III subunit epsilon; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.735 |
| ABK75344.1 | recA | MSMEG_6275 | MSMEG_2723 | DNA polymerase III subunit epsilon; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...] | 0.613 |
| dinB-3 | ABK70918.1 | MSMEG_3172 | MSMEG_4925 | DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Transcriptional regulator, Ada family protein/DNA-3-methyladenine glycosylase II; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | 0.848 |
| dinB-3 | ABK75344.1 | MSMEG_3172 | MSMEG_6275 | DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III subunit epsilon; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | 0.716 |
| dinB-3 | dnaE2 | MSMEG_3172 | MSMEG_1633 | DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.931 |
| dinB-3 | dnaN | MSMEG_3172 | MSMEG_0001 | DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.967 |
| dinB-3 | lexA | MSMEG_3172 | MSMEG_2740 | DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.952 |
| dinB-3 | ligD-2 | MSMEG_3172 | MSMEG_5570 | DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA ligase; With Ku forms a non-homologous end joining (NHEJ) repair enzyme which repairs blunt-end and 5'-overhang DNA double strand breaks (DSB) with about 50% fidelity, and DSB with non-complementary 3' ends. Plays a partial role in NHEJ during 3'-overhang repair. NHEJ repairs DSB with blunt ends and 5' overhangs with a high level of nucleotide insertion/deletion, without a need for microhomology. Acts as a DNA ligase on singly nicked dsDNA, as a DNA-directed DNA polymerase on 5' overhangs, and adds non-templated nucleotides to 3' overhangs (terminal transferase). Fills in gaps in d [...] | 0.767 |
| dinB-3 | polA | MSMEG_3172 | MSMEG_3839 | DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.918 |
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