node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK72015.1 | ABK72022.1 | MSMEG_6153 | MSMEG_3178 | DNA polymerase III subunit delta; Identified by match to protein family HMM TIGR00678. | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | 0.981 |
ABK72015.1 | ABK72472.1 | MSMEG_6153 | MSMEG_4572 | DNA polymerase III subunit delta; Identified by match to protein family HMM TIGR00678. | DNA polymerase III, delta subunit; Identified by match to protein family HMM PF06144. | 0.994 |
ABK72015.1 | ABK75344.1 | MSMEG_6153 | MSMEG_6275 | DNA polymerase III subunit delta; Identified by match to protein family HMM TIGR00678. | DNA polymerase III subunit epsilon; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | 0.973 |
ABK72015.1 | dnaG | MSMEG_6153 | MSMEG_4482 | DNA polymerase III subunit delta; Identified by match to protein family HMM TIGR00678. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.769 |
ABK72015.1 | dnaN | MSMEG_6153 | MSMEG_0001 | DNA polymerase III subunit delta; Identified by match to protein family HMM TIGR00678. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.991 |
ABK72015.1 | dnaX | MSMEG_6153 | MSMEG_6285 | DNA polymerase III subunit delta; Identified by match to protein family HMM TIGR00678. | DNA polymerase III gamma/tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.923 |
ABK72015.1 | secA | MSMEG_6153 | MSMEG_1881 | DNA polymerase III subunit delta; Identified by match to protein family HMM TIGR00678. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.435 |
ABK72022.1 | ABK72015.1 | MSMEG_3178 | MSMEG_6153 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA polymerase III subunit delta; Identified by match to protein family HMM TIGR00678. | 0.981 |
ABK72022.1 | ABK72472.1 | MSMEG_3178 | MSMEG_4572 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA polymerase III, delta subunit; Identified by match to protein family HMM PF06144. | 0.988 |
ABK72022.1 | ABK75344.1 | MSMEG_3178 | MSMEG_6275 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA polymerase III subunit epsilon; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | 0.974 |
ABK72022.1 | ABK76147.1 | MSMEG_3178 | MSMEG_2690 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA translocase FtsK; Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. | 0.847 |
ABK72022.1 | dnaG | MSMEG_3178 | MSMEG_4482 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.859 |
ABK72022.1 | dnaN | MSMEG_3178 | MSMEG_0001 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.998 |
ABK72022.1 | dnaX | MSMEG_3178 | MSMEG_6285 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA polymerase III gamma/tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.978 |
ABK72022.1 | recA | MSMEG_3178 | MSMEG_2723 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...] | 0.925 |
ABK72022.1 | rpoB | MSMEG_3178 | MSMEG_1367 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription. | 0.884 |
ABK72022.1 | secA | MSMEG_3178 | MSMEG_1881 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.897 |
ABK72472.1 | ABK72015.1 | MSMEG_4572 | MSMEG_6153 | DNA polymerase III, delta subunit; Identified by match to protein family HMM PF06144. | DNA polymerase III subunit delta; Identified by match to protein family HMM TIGR00678. | 0.994 |
ABK72472.1 | ABK72022.1 | MSMEG_4572 | MSMEG_3178 | DNA polymerase III, delta subunit; Identified by match to protein family HMM PF06144. | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594. | 0.988 |
ABK72472.1 | ABK75344.1 | MSMEG_4572 | MSMEG_6275 | DNA polymerase III, delta subunit; Identified by match to protein family HMM PF06144. | DNA polymerase III subunit epsilon; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | 0.953 |