node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK73019.1 | ABK76159.1 | MSMEG_3195 | MSMEG_3196 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.879 |
ABK73019.1 | bioB | MSMEG_3195 | MSMEG_3194 | Conserved hypothetical protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.939 |
ABK73019.1 | bioD | MSMEG_3195 | MSMEG_3190 | Conserved hypothetical protein. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.453 |
ABK73623.1 | ABK74700.1 | MSMEG_2738 | MSMEG_1822 | Biotin sulfoxide reductase; Identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | biotin-[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | 0.908 |
ABK73623.1 | bioB | MSMEG_2738 | MSMEG_3194 | Biotin sulfoxide reductase; Identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.900 |
ABK74253.1 | bioB | MSMEG_1662 | MSMEG_3194 | Taurine-pyruvate aminotransferase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.693 |
ABK74253.1 | bioD | MSMEG_1662 | MSMEG_3190 | Taurine-pyruvate aminotransferase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.683 |
ABK74253.1 | bioF | MSMEG_1662 | MSMEG_3189 | Taurine-pyruvate aminotransferase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.543 |
ABK74253.1 | nadE | MSMEG_1662 | MSMEG_4617 | Taurine-pyruvate aminotransferase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.423 |
ABK74700.1 | ABK73623.1 | MSMEG_1822 | MSMEG_2738 | biotin-[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | Biotin sulfoxide reductase; Identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.908 |
ABK74700.1 | bioA | MSMEG_1822 | MSMEG_3188 | biotin-[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.732 |
ABK74700.1 | bioB | MSMEG_1822 | MSMEG_3194 | biotin-[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.980 |
ABK74700.1 | bioD | MSMEG_1822 | MSMEG_3190 | biotin-[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.775 |
ABK74700.1 | nadE | MSMEG_1822 | MSMEG_4617 | biotin-[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.788 |
ABK76159.1 | ABK73019.1 | MSMEG_3196 | MSMEG_3195 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.879 |
ABK76159.1 | bioB | MSMEG_3196 | MSMEG_3194 | Conserved hypothetical protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.893 |
bioA | ABK74700.1 | MSMEG_3188 | MSMEG_1822 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | biotin-[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | 0.732 |
bioA | bioB | MSMEG_3188 | MSMEG_3194 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.998 |
bioA | bioD | MSMEG_3188 | MSMEG_3190 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.999 |
bioA | bioF | MSMEG_3188 | MSMEG_3189 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.999 |