STRINGSTRING
ABK70834.1 ABK70834.1 ABK74419.1 ABK74419.1 rshA rshA rseA rseA ABK69932.1 ABK69932.1 ABK74333.1 ABK74333.1 ABK72765.1 ABK72765.1 ABK74737.1 ABK74737.1 ABK75875.1 ABK75875.1 rpoC rpoC rpoB rpoB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK70834.1RNA polymerase sigma factor, sigma-70 family protein; Identified by match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily. (208 aa)    
Predicted Functional Partners:
ABK74419.1
Conserved hypothetical protein.
  
 
 0.502
rshA
Anti-sigma factor, family protein; A redox-regulated anti-sigma factor for cognate extracytoplasmic function (ECF) sigma factor SigH. ECF sigma factors are held in an inactive form by an anti-sigma factor (Probable). Overexpression leads to increased susceptibility to diamide.
  
 
 0.493
rseA
Conserved hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigE. ECF sigma factors are held in an inactive form by an anti-sigma factor (By similarity); Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily.
  
 
 0.491
ABK69932.1
Integral membrane protein.
 
    0.460
ABK74333.1
dTDP-glucose 4,6-dehydratase.
  
    0.459
ABK72765.1
HAD-superfamily protein hydrolase, subfamily protein IIA; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460; Belongs to the HAD-like hydrolase superfamily.
 
    0.440
ABK74737.1
Anti-sigm factor, ChrR.
  
 
 0.426
ABK75875.1
Integral membrane protein; Identified by match to protein family HMM PF00892.
  
    0.418
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.415
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription.
  
 
 0.410
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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