node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69574.1 | ABK76108.1 | MSMEG_5670 | MSMEG_3283 | Efflux membrane protein; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily. | Membrane transport protein; Identified by match to protein family HMM PF07690. | 0.402 |
ABK69661.1 | ABK76108.1 | MSMEG_2848 | MSMEG_3283 | Transmembrane efflux protein; Identified by match to protein family HMM PF07690. | Membrane transport protein; Identified by match to protein family HMM PF07690. | 0.760 |
ABK70052.1 | ABK76108.1 | MSMEG_3284 | MSMEG_3283 | Transcriptional regulator, MarR family protein; Identified by match to protein family HMM PF01047. | Membrane transport protein; Identified by match to protein family HMM PF07690. | 0.524 |
ABK70138.1 | ABK72530.1 | MSMEG_3405 | MSMEG_3815 | Identified by match to protein family HMM PF07690. | Possible drug efflux membrane protein; Identified by match to protein family HMM PF07690. | 0.727 |
ABK70138.1 | ABK76108.1 | MSMEG_3405 | MSMEG_3283 | Identified by match to protein family HMM PF07690. | Membrane transport protein; Identified by match to protein family HMM PF07690. | 0.755 |
ABK72530.1 | ABK70138.1 | MSMEG_3815 | MSMEG_3405 | Possible drug efflux membrane protein; Identified by match to protein family HMM PF07690. | Identified by match to protein family HMM PF07690. | 0.727 |
ABK72530.1 | ABK76108.1 | MSMEG_3815 | MSMEG_3283 | Possible drug efflux membrane protein; Identified by match to protein family HMM PF07690. | Membrane transport protein; Identified by match to protein family HMM PF07690. | 0.594 |
ABK72530.1 | lfrA | MSMEG_3815 | MSMEG_6225 | Possible drug efflux membrane protein; Identified by match to protein family HMM PF07690. | Proton antiporter efflux pump; Energy-dependent efflux pump that contributes to drug resistance. Catalyzes the efflux of norfloxacin and several related fluoroquinolones (FQ). Contributes significantly to the intrinsic MICs for ethidium bromide and acriflavine. Overexpression confers low-level resistance to hydrophilic FQ such as ciprofloxacin, ofloxacin and levofloxacin, and to ethidium bromide, acridine, acriflavine, rhodamine 123 and some quaternary ammonium compounds. May contribute to resistance to certain beta-lactams. Probably uses the proton motive force. | 0.650 |
ABK73376.1 | ABK76108.1 | MSMEG_0090 | MSMEG_3283 | Conserved hypothetical protein. | Membrane transport protein; Identified by match to protein family HMM PF07690. | 0.411 |
ABK76108.1 | ABK69574.1 | MSMEG_3283 | MSMEG_5670 | Membrane transport protein; Identified by match to protein family HMM PF07690. | Efflux membrane protein; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily. | 0.402 |
ABK76108.1 | ABK69661.1 | MSMEG_3283 | MSMEG_2848 | Membrane transport protein; Identified by match to protein family HMM PF07690. | Transmembrane efflux protein; Identified by match to protein family HMM PF07690. | 0.760 |
ABK76108.1 | ABK70052.1 | MSMEG_3283 | MSMEG_3284 | Membrane transport protein; Identified by match to protein family HMM PF07690. | Transcriptional regulator, MarR family protein; Identified by match to protein family HMM PF01047. | 0.524 |
ABK76108.1 | ABK70138.1 | MSMEG_3283 | MSMEG_3405 | Membrane transport protein; Identified by match to protein family HMM PF07690. | Identified by match to protein family HMM PF07690. | 0.755 |
ABK76108.1 | ABK72530.1 | MSMEG_3283 | MSMEG_3815 | Membrane transport protein; Identified by match to protein family HMM PF07690. | Possible drug efflux membrane protein; Identified by match to protein family HMM PF07690. | 0.594 |
ABK76108.1 | ABK73376.1 | MSMEG_3283 | MSMEG_0090 | Membrane transport protein; Identified by match to protein family HMM PF07690. | Conserved hypothetical protein. | 0.411 |
ABK76108.1 | lfrA | MSMEG_3283 | MSMEG_6225 | Membrane transport protein; Identified by match to protein family HMM PF07690. | Proton antiporter efflux pump; Energy-dependent efflux pump that contributes to drug resistance. Catalyzes the efflux of norfloxacin and several related fluoroquinolones (FQ). Contributes significantly to the intrinsic MICs for ethidium bromide and acriflavine. Overexpression confers low-level resistance to hydrophilic FQ such as ciprofloxacin, ofloxacin and levofloxacin, and to ethidium bromide, acridine, acriflavine, rhodamine 123 and some quaternary ammonium compounds. May contribute to resistance to certain beta-lactams. Probably uses the proton motive force. | 0.717 |
lfrA | ABK72530.1 | MSMEG_6225 | MSMEG_3815 | Proton antiporter efflux pump; Energy-dependent efflux pump that contributes to drug resistance. Catalyzes the efflux of norfloxacin and several related fluoroquinolones (FQ). Contributes significantly to the intrinsic MICs for ethidium bromide and acriflavine. Overexpression confers low-level resistance to hydrophilic FQ such as ciprofloxacin, ofloxacin and levofloxacin, and to ethidium bromide, acridine, acriflavine, rhodamine 123 and some quaternary ammonium compounds. May contribute to resistance to certain beta-lactams. Probably uses the proton motive force. | Possible drug efflux membrane protein; Identified by match to protein family HMM PF07690. | 0.650 |
lfrA | ABK76108.1 | MSMEG_6225 | MSMEG_3283 | Proton antiporter efflux pump; Energy-dependent efflux pump that contributes to drug resistance. Catalyzes the efflux of norfloxacin and several related fluoroquinolones (FQ). Contributes significantly to the intrinsic MICs for ethidium bromide and acriflavine. Overexpression confers low-level resistance to hydrophilic FQ such as ciprofloxacin, ofloxacin and levofloxacin, and to ethidium bromide, acridine, acriflavine, rhodamine 123 and some quaternary ammonium compounds. May contribute to resistance to certain beta-lactams. Probably uses the proton motive force. | Membrane transport protein; Identified by match to protein family HMM PF07690. | 0.717 |