STRINGSTRING
ABK76108.1 ABK76108.1 ABK69661.1 ABK69661.1 ABK70138.1 ABK70138.1 lfrA lfrA ABK72530.1 ABK72530.1 ABK70052.1 ABK70052.1 ABK73376.1 ABK73376.1 ABK69574.1 ABK69574.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK76108.1Membrane transport protein; Identified by match to protein family HMM PF07690. (488 aa)    
Predicted Functional Partners:
ABK69661.1
Transmembrane efflux protein; Identified by match to protein family HMM PF07690.
 
  
 0.760
ABK70138.1
Identified by match to protein family HMM PF07690.
  
     0.755
lfrA
Proton antiporter efflux pump; Energy-dependent efflux pump that contributes to drug resistance. Catalyzes the efflux of norfloxacin and several related fluoroquinolones (FQ). Contributes significantly to the intrinsic MICs for ethidium bromide and acriflavine. Overexpression confers low-level resistance to hydrophilic FQ such as ciprofloxacin, ofloxacin and levofloxacin, and to ethidium bromide, acridine, acriflavine, rhodamine 123 and some quaternary ammonium compounds. May contribute to resistance to certain beta-lactams. Probably uses the proton motive force.
 
   
 0.717
ABK72530.1
Possible drug efflux membrane protein; Identified by match to protein family HMM PF07690.
  
    0.594
ABK70052.1
Transcriptional regulator, MarR family protein; Identified by match to protein family HMM PF01047.
  
  
 0.524
ABK73376.1
Conserved hypothetical protein.
  
  
 0.411
ABK69574.1
Efflux membrane protein; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily.
 
  
0.402
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (22%) [HD]