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ABK71991.1 ABK71991.1 carD carD ABK72536.1 ABK72536.1 tuf tuf etfB etfB ABK72599.1 ABK72599.1 cspA cspA rpsA rpsA ABK72067.1 ABK72067.1 ABK73823.1 ABK73823.1 ABK74218.1 ABK74218.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK71991.1Oxidoreductase, FAD/FMN-binding; Identified by match to protein family HMM PF00724. (372 aa)    
Predicted Functional Partners:
carD
Transcriptional regulator, CarD family protein; Controls rRNA transcription by binding to the RNA polymerase (RNAP). Required for the stringent response to starvation, oxidative and genotoxic stresses as well as control of rRNA under normal growth conditions.
  
    0.553
ABK72536.1
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.468
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
  
 0.459
etfB
Electron transfer flavoprotein, beta subunit; Identified by similarity to SP:O85691; match to protein family HMM PF01012.
  
 
 0.459
ABK72599.1
Conserved domain protein; Identified by match to protein family HMM PF00313.
  
  
 0.446
cspA
Conserved domain protein; Identified by match to protein family HMM PF00313.
  
  
 0.444
rpsA
30S ribosomal protein S1; Binds mRNA, facilitating recognition of most mRNAs by the 30S ribosomal subunit during translation initiation (By similarity). Plays a role in trans-translation; binds tmRNA (the product of the ssrA gene). Binds very poorly to pyrazinoic acid (POA), the active form of the prodrug pyrazinamide (PZA); POA does not disrupt trans-translation in this organism. M.smegmatis is resistant to the antibiotic PZA. In trans-translation Ala-aminoacylated transfer-messenger RNA (tmRNA, product of the ssrA gene; the 2 termini fold to resemble tRNA(Ala) while it encodes a shor [...]
  
    0.439
ABK72067.1
FMN-dependent dehydrogenase; Identified by match to protein family HMM PF01070.
  
  
 0.432
ABK73823.1
Hydrolase; Identified by match to protein family HMM PF00561.
  
  
 0.429
ABK74218.1
Lactate 2-monooxygenase; Identified by match to protein family HMM PF01070.
  
  
 0.429
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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