STRINGSTRING
ABK74850.1 ABK74850.1 ABK73508.1 ABK73508.1 ABK73530.1 ABK73530.1 ABK71831.1 ABK71831.1 ABK71306.1 ABK71306.1 ABK72424.1 ABK72424.1 ABK73111.1 ABK73111.1 ABK72083.1 ABK72083.1 saeB saeB recA recA mfpA mfpA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
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Experiments
Databases
Textmining
[Homology]
Score
ABK74850.1Conserved hypothetical protein. (200 aa)    
Predicted Functional Partners:
ABK73508.1
Conserved hypothetical protein; Identified by match to protein family HMM PF03883; Belongs to the UPF0246 family.
  
    0.631
ABK73530.1
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.584
ABK71831.1
Conserved hypothetical protein.
  
 
 0.424
ABK71306.1
Conserved hypothetical protein.
  
 
 0.422
ABK72424.1
Conserved hypothetical protein.
  
 
 0.422
ABK73111.1
Conserved hypothetical protein.
  
 
 0.416
ABK72083.1
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.416
saeB
Hypothetical protein; May be involved in assembly of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Involved in DNA conjugation in recipient (MDK8) but not donor (mc(2)155) strain.
  
 
 0.415
recA
Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...]
  
  
 0.411
mfpA
Conserved hypothetical protein; When present on multicopy plasmids confers increased resistance to fluoroquinolone antibiotics such as ciprofloxacin and sparfloxacin but not the quinolone nalidixic acid. Forms a structure that exhibits size, shape and electrostatic similarity to B-form DNA; it may bind to DNA gyrase which is postulated to protect it from fluoroquinolones (By similarity). Belongs to the pentapeptide repeat protein family.
   
 
 0.408
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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