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glcB glcB aceA aceA aceA-2 aceA-2 pta pta mqo mqo fumC fumC gltA gltA ABK73929.1 ABK73929.1 ABK75407.1 ABK75407.1 ABK73320.1 ABK73320.1 ABK72632.1 ABK72632.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (721 aa)    
Predicted Functional Partners:
aceA
Isocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346.
 
 
 0.999
aceA-2
Isocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346.
 
 
 0.995
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.982
mqo
Malate:quinone-oxidoreductase; Identified by match to protein family HMM PF01266; match to protein family HMM PF06039; match to protein family HMM TIGR01320.
   
 
 0.976
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.976
gltA
Citrate synthase I; Identified by similarity to SP:P42457; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family.
  
 0.973
ABK73929.1
Citrate synthase 2; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.
  
 0.973
ABK75407.1
Citrate synthase; Identified by match to protein family HMM PF00285; Belongs to the citrate synthase family.
  
 0.963
ABK73320.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.955
ABK72632.1
AMP-dependent synthetase and ligase; Identified by match to protein family HMM PF00501.
  
 0.953
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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