STRINGSTRING
nadK nadK ABK71205.1 ABK71205.1 nadE nadE ABK74298.1 ABK74298.1 ABK71513.1 ABK71513.1 nadD nadD ABK71721.1 ABK71721.1 sir2 sir2 ABK74118.1 ABK74118.1 pntA pntA ABK71348.1 ABK71348.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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nadKInorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NADkinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (307 aa)    
Predicted Functional Partners:
ABK71205.1
Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478.
  
  
 0.996
nadE
Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.962
ABK74298.1
TPR-repeat-containing protein.
 
  
 0.959
ABK71513.1
Conserved hypothetical protein.
  
  
 0.955
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.953
ABK71721.1
Hydrolase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460.
  
  
 0.951
sir2
NAD-dependent deacetylase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.
  
 
 0.923
ABK74118.1
PntAB protein.
   
 
 0.918
pntA
NAD(P) transhydrogenase, alpha subunit; Identified by similarity to SP:P07001; match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00561.
     
 0.910
ABK71348.1
Alanine dehydrogenase/pyridine nucleotide transhydrogenase; Identified by match to protein family HMM PF01262; match to protein family HMM PF05222.
     
 0.910
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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