STRINGSTRING
ABK71205.1 ABK71205.1 nadK nadK ABK71513.1 ABK71513.1 ABK74298.1 ABK74298.1 ABK71721.1 ABK71721.1 gidB gidB ABK71018.1 ABK71018.1 gyrA gyrA ABK71293.1 ABK71293.1 rpoB rpoB ABK76102.1 ABK76102.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK71205.1Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478. (269 aa)    
Predicted Functional Partners:
nadK
Inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NADkinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.996
ABK71513.1
Conserved hypothetical protein.
  
  
 0.913
ABK74298.1
TPR-repeat-containing protein.
  
  
 0.908
ABK71721.1
Hydrolase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460.
  
  
 0.904
gidB
Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 518 of 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.822
ABK71018.1
Conserved hypothetical protein.
  
  
 0.820
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.799
ABK71293.1
23s ribosomal RNA methyltransferase; Identified by match to protein family HMM PF00588.
  
  
 0.792
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription.
  
  
 0.791
ABK76102.1
Nicotinamidase/pyrazinamidase; Identified by match to protein family HMM PF00857.
  
  
 0.789
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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