node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK72199.1 | ABK73065.1 | MSMEG_1515 | MSMEG_1051 | Two-component sensor histidine kinase; Identified by match to protein family HMM PF00027; match to protein family HMM PF02518. | Immunogenic protein MPB64/MPT64. | 0.610 |
ABK72199.1 | ABK74003.1 | MSMEG_1515 | MSMEG_3801 | Two-component sensor histidine kinase; Identified by match to protein family HMM PF00027; match to protein family HMM PF02518. | Conserved hypothetical protein. | 0.728 |
ABK72199.1 | ABK75360.1 | MSMEG_1515 | MSMEG_2331 | Two-component sensor histidine kinase; Identified by match to protein family HMM PF00027; match to protein family HMM PF02518. | Immunogenic protein MPB64/MPT64. | 0.612 |
ABK72199.1 | dnaJ | MSMEG_1515 | MSMEG_0711 | Two-component sensor histidine kinase; Identified by match to protein family HMM PF00027; match to protein family HMM PF02518. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.616 |
ABK72199.1 | rpoA | MSMEG_1515 | MSMEG_1524 | Two-component sensor histidine kinase; Identified by match to protein family HMM PF00027; match to protein family HMM PF02518. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.658 |
ABK72199.1 | rpoB | MSMEG_1515 | MSMEG_1367 | Two-component sensor histidine kinase; Identified by match to protein family HMM PF00027; match to protein family HMM PF02518. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription. | 0.605 |
ABK72199.1 | rpoZ | MSMEG_1515 | MSMEG_3053 | Two-component sensor histidine kinase; Identified by match to protein family HMM PF00027; match to protein family HMM PF02518. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.492 |
ABK72199.1 | saeC | MSMEG_1515 | MSMEG_0046 | Two-component sensor histidine kinase; Identified by match to protein family HMM PF00027; match to protein family HMM PF02518. | Conserved hypothetical protein; May be involved in assembly of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Involved in DNA conjugation in recipient (MKD8) strain. | 0.814 |
ABK73065.1 | ABK72199.1 | MSMEG_1051 | MSMEG_1515 | Immunogenic protein MPB64/MPT64. | Two-component sensor histidine kinase; Identified by match to protein family HMM PF00027; match to protein family HMM PF02518. | 0.610 |
ABK73065.1 | ABK74003.1 | MSMEG_1051 | MSMEG_3801 | Immunogenic protein MPB64/MPT64. | Conserved hypothetical protein. | 0.736 |
ABK73065.1 | alaS | MSMEG_1051 | MSMEG_3025 | Immunogenic protein MPB64/MPT64. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.913 |
ABK73065.1 | rpoA | MSMEG_1051 | MSMEG_1524 | Immunogenic protein MPB64/MPT64. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.801 |
ABK73065.1 | rpoB | MSMEG_1051 | MSMEG_1367 | Immunogenic protein MPB64/MPT64. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription. | 0.801 |
ABK73065.1 | rpoZ | MSMEG_1051 | MSMEG_3053 | Immunogenic protein MPB64/MPT64. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.799 |
ABK73065.1 | saeC | MSMEG_1051 | MSMEG_0046 | Immunogenic protein MPB64/MPT64. | Conserved hypothetical protein; May be involved in assembly of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Involved in DNA conjugation in recipient (MKD8) strain. | 0.712 |
ABK74003.1 | ABK72199.1 | MSMEG_3801 | MSMEG_1515 | Conserved hypothetical protein. | Two-component sensor histidine kinase; Identified by match to protein family HMM PF00027; match to protein family HMM PF02518. | 0.728 |
ABK74003.1 | ABK73065.1 | MSMEG_3801 | MSMEG_1051 | Conserved hypothetical protein. | Immunogenic protein MPB64/MPT64. | 0.736 |
ABK74003.1 | ABK75360.1 | MSMEG_3801 | MSMEG_2331 | Conserved hypothetical protein. | Immunogenic protein MPB64/MPT64. | 0.739 |
ABK74003.1 | ABK75614.1 | MSMEG_3801 | MSMEG_3802 | Conserved hypothetical protein. | Identified by match to protein family HMM PF07721. | 0.776 |
ABK74003.1 | alaS | MSMEG_3801 | MSMEG_3025 | Conserved hypothetical protein. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.868 |