node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70225.1 | lnt | MSMEG_6109 | MSMEG_3860 | LpqG protein; Identified by match to protein family HMM PF04402. | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | 0.607 |
ABK70225.1 | lspA | MSMEG_6109 | MSMEG_3174 | LpqG protein; Identified by match to protein family HMM PF04402. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins. | 0.408 |
ABK71706.1 | lnt | MSMEG_0248 | MSMEG_3860 | Conserved hypothetical protein; Identified by match to protein family HMM PF03706; match to protein family HMM TIGR00374. | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | 0.639 |
ABK73064.1 | ABK73409.1 | MSMEG_3861 | MSMEG_3862 | Amidohydrolase 3; Identified by match to protein family HMM PF07969. | FxsA cytoplasmic membrane protein; Identified by match to protein family HMM PF04186. | 0.870 |
ABK73064.1 | cobN | MSMEG_3861 | MSMEG_3864 | Amidohydrolase 3; Identified by match to protein family HMM PF07969. | Cobaltochelatase, CobN subunit; Identified by match to protein family HMM PF02514; match to protein family HMM TIGR02257. | 0.512 |
ABK73064.1 | lnt | MSMEG_3861 | MSMEG_3860 | Amidohydrolase 3; Identified by match to protein family HMM PF07969. | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | 0.916 |
ABK73064.1 | ppm1 | MSMEG_3861 | MSMEG_3859 | Amidohydrolase 3; Identified by match to protein family HMM PF07969. | Glycosyl transferase, group 2 family protein; Transfers mannose from GDP-mannose to lipid acceptors to form polyprenol monophosphomannose (PPM); catalytic activity in vitro is enhanced by Lnt (AC A0QZ13). PMM is an alkai-stable sugar donor which adds mannose-phosphate residues to triacylated-PIM2, eventually leading to generation of the cell wall glycolipid lipoglycan modulins lipoarabinomannan (LAM) and lipomannan (LM) (By similarity). | 0.905 |
ABK73409.1 | ABK73064.1 | MSMEG_3862 | MSMEG_3861 | FxsA cytoplasmic membrane protein; Identified by match to protein family HMM PF04186. | Amidohydrolase 3; Identified by match to protein family HMM PF07969. | 0.870 |
ABK73409.1 | cobN | MSMEG_3862 | MSMEG_3864 | FxsA cytoplasmic membrane protein; Identified by match to protein family HMM PF04186. | Cobaltochelatase, CobN subunit; Identified by match to protein family HMM PF02514; match to protein family HMM TIGR02257. | 0.631 |
ABK73409.1 | lnt | MSMEG_3862 | MSMEG_3860 | FxsA cytoplasmic membrane protein; Identified by match to protein family HMM PF04186. | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | 0.834 |
ABK73409.1 | ppm1 | MSMEG_3862 | MSMEG_3859 | FxsA cytoplasmic membrane protein; Identified by match to protein family HMM PF04186. | Glycosyl transferase, group 2 family protein; Transfers mannose from GDP-mannose to lipid acceptors to form polyprenol monophosphomannose (PPM); catalytic activity in vitro is enhanced by Lnt (AC A0QZ13). PMM is an alkai-stable sugar donor which adds mannose-phosphate residues to triacylated-PIM2, eventually leading to generation of the cell wall glycolipid lipoglycan modulins lipoarabinomannan (LAM) and lipomannan (LM) (By similarity). | 0.797 |
cobN | ABK73064.1 | MSMEG_3864 | MSMEG_3861 | Cobaltochelatase, CobN subunit; Identified by match to protein family HMM PF02514; match to protein family HMM TIGR02257. | Amidohydrolase 3; Identified by match to protein family HMM PF07969. | 0.512 |
cobN | ABK73409.1 | MSMEG_3864 | MSMEG_3862 | Cobaltochelatase, CobN subunit; Identified by match to protein family HMM PF02514; match to protein family HMM TIGR02257. | FxsA cytoplasmic membrane protein; Identified by match to protein family HMM PF04186. | 0.631 |
cobN | lnt | MSMEG_3864 | MSMEG_3860 | Cobaltochelatase, CobN subunit; Identified by match to protein family HMM PF02514; match to protein family HMM TIGR02257. | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | 0.596 |
cobN | ppm1 | MSMEG_3864 | MSMEG_3859 | Cobaltochelatase, CobN subunit; Identified by match to protein family HMM PF02514; match to protein family HMM TIGR02257. | Glycosyl transferase, group 2 family protein; Transfers mannose from GDP-mannose to lipid acceptors to form polyprenol monophosphomannose (PPM); catalytic activity in vitro is enhanced by Lnt (AC A0QZ13). PMM is an alkai-stable sugar donor which adds mannose-phosphate residues to triacylated-PIM2, eventually leading to generation of the cell wall glycolipid lipoglycan modulins lipoarabinomannan (LAM) and lipomannan (LM) (By similarity). | 0.600 |
glnD | lnt | MSMEG_2427 | MSMEG_3860 | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | 0.583 |
lgt | lnt | MSMEG_5408 | MSMEG_3860 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | 0.889 |
lgt | lspA | MSMEG_5408 | MSMEG_3174 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins. | 0.924 |
lgt-2 | lnt | MSMEG_3222 | MSMEG_3860 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | 0.904 |
lgt-2 | lspA | MSMEG_3222 | MSMEG_3174 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins. | 0.942 |