STRINGSTRING
ectA ectA ectB ectB ectC ectC thpD thpD ABK70707.1 ABK70707.1 ABK75975.1 ABK75975.1 ABK73423.1 ABK73423.1 ABK72770.1 ABK72770.1 dop dop ABK75094.1 ABK75094.1 ABK70537.1 ABK70537.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ectAL-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (177 aa)    
Predicted Functional Partners:
ectB
Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.998
ectC
Ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.
 
 
  0.989
thpD
Ectoine hydroxylase; Identified by match to protein family HMM PF05721; match to protein family HMM TIGR02408.
 
    0.880
ABK70707.1
Xaa-Pro aminopeptidase; Identified by match to protein family HMM PF00557.
  
     0.609
ABK75975.1
Oxidoreductase, short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.604
ABK73423.1
Membrane protein, MmpL family protein; Identified by match to protein family HMM PF03176.
   
  
 0.591
ABK72770.1
Cis-3-chloroacrylic acid dehalogenase, putative; Identified by match to protein family HMM PF01361.
      
 0.586
dop
Proteasome component; Specifically catalyzes the deamidation of the C-terminal glutamine of the prokaryotic ubiquitin-like protein Pup to glutamate, thereby rendering Pup competent for conjugation. Probably also displays depupylase (DPUP) activity, removing conjugated Pup from target proteins; thus may be involved in the recycling of Pup and may function similarly to deubiquitinases (DUBs) in eukaryotes to prevent or promote proteasomal degradation of certain proteins. Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.
  
    0.496
ABK75094.1
Cyclopropane-fatty-acyl-phospholipid synthase 1; Identified by match to protein family HMM PF02353.
   
  
 0.428
ABK70537.1
Cyclopropane-fatty-acyl-phospholipid synthase 1; Identified by match to protein family HMM PF02353.
   
  
 0.428
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.