node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69757.1 | ABK71214.1 | MSMEG_3908 | MSMEG_3907 | Conserved hypothetical protein. | RecB family protein exonuclease. | 0.805 |
ABK69757.1 | ABK71254.1 | MSMEG_3908 | MSMEG_3910 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.791 |
ABK69757.1 | ABK76023.1 | MSMEG_3908 | MSMEG_3906 | Conserved hypothetical protein. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.611 |
ABK71214.1 | ABK69757.1 | MSMEG_3907 | MSMEG_3908 | RecB family protein exonuclease. | Conserved hypothetical protein. | 0.805 |
ABK71214.1 | ABK71254.1 | MSMEG_3907 | MSMEG_3910 | RecB family protein exonuclease. | Conserved hypothetical protein. | 0.790 |
ABK71214.1 | ABK75351.1 | MSMEG_3907 | MSMEG_6892 | RecB family protein exonuclease. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.587 |
ABK71214.1 | ABK76023.1 | MSMEG_3907 | MSMEG_3906 | RecB family protein exonuclease. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.667 |
ABK71214.1 | dop | MSMEG_3907 | MSMEG_3897 | RecB family protein exonuclease. | Proteasome component; Specifically catalyzes the deamidation of the C-terminal glutamine of the prokaryotic ubiquitin-like protein Pup to glutamate, thereby rendering Pup competent for conjugation. Probably also displays depupylase (DPUP) activity, removing conjugated Pup from target proteins; thus may be involved in the recycling of Pup and may function similarly to deubiquitinases (DUBs) in eukaryotes to prevent or promote proteasomal degradation of certain proteins. Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily. | 0.532 |
ABK71214.1 | nucS | MSMEG_3907 | MSMEG_4923 | RecB family protein exonuclease. | Conserved hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. | 0.590 |
ABK71214.1 | pafA | MSMEG_3907 | MSMEG_3890 | RecB family protein exonuclease. | Proteasome component; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction likely involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine. Belongs to the Pup ligase/Pup deamidase family. Pup- conjugating enzyme subfamily. | 0.560 |
ABK71214.1 | pimA | MSMEG_3907 | MSMEG_2935 | RecB family protein exonuclease. | Phosphatidylinositol alpha-mannosyltransferase; Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). In contrary to PimB, the mannosyltransferase PimA is unable to transfer a mannose residue to the position 6 of the phosphatidyl-myo-inos [...] | 0.531 |
ABK71214.1 | thyX | MSMEG_3907 | MSMEG_2683 | RecB family protein exonuclease. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.724 |
ABK71214.1 | whiB3 | MSMEG_3907 | MSMEG_1597 | RecB family protein exonuclease. | Transcription factor WhiB; A redox-sensitive transcriptional regulator. Maintains intracellular redox homeostasis by regulating catabolic metabolism and polyketide biosynthesis. Regulates expression of the redox buffer ergothioneine (ERG). In concert with myothiol (MSH), another redox buffer, responds to low pH leading to acid resistance. The apo- but not holo-form probably binds DNA (By similarity). | 0.566 |
ABK71254.1 | ABK69757.1 | MSMEG_3910 | MSMEG_3908 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.791 |
ABK71254.1 | ABK71214.1 | MSMEG_3910 | MSMEG_3907 | Conserved hypothetical protein. | RecB family protein exonuclease. | 0.790 |
ABK71254.1 | ABK76023.1 | MSMEG_3910 | MSMEG_3906 | Conserved hypothetical protein. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.572 |
ABK75351.1 | ABK71214.1 | MSMEG_6892 | MSMEG_3907 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | RecB family protein exonuclease. | 0.587 |
ABK76023.1 | ABK69757.1 | MSMEG_3906 | MSMEG_3908 | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | Conserved hypothetical protein. | 0.611 |
ABK76023.1 | ABK71214.1 | MSMEG_3906 | MSMEG_3907 | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | RecB family protein exonuclease. | 0.667 |
ABK76023.1 | ABK71254.1 | MSMEG_3906 | MSMEG_3910 | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | Conserved hypothetical protein. | 0.572 |