STRINGSTRING
ABK72133.1 ABK72133.1 otsB otsB otsA otsA ABK75395.1 ABK75395.1 treS treS treZ treZ ABK72415.1 ABK72415.1 ABK69716.1 ABK69716.1 ABK71596.1 ABK71596.1 ABK75698.1 ABK75698.1 ABK74424.1 ABK74424.1
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query proteins and first shell of interactors
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second shell of interactors
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Predicted Interactions
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textmining
co-expression
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Score
ABK72133.1Trehalose 6-phosphate phosphorylase; Identified by match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636. (906 aa)    
Predicted Functional Partners:
otsB
Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
  
 
 0.884
otsA
Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Involved in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1- phosphate (M1P), and probably in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to glucose-6-phosphate (Glc-6-P) to form trehalose-6-phosphate. ADP-Glc, CDP-Glc, GDP- Glc and TDP-Glc are also glucosyl donors, however, when the pyrimidine sugar nucleotides (CDP-Glc, TDP-Glc and UDP-Glc) are used as substrates, there is an absolute requirement [...]
 
   
 0.863
ABK75395.1
Conserved hypothetical protein.
  
    0.760
treS
Trehalose synthase; Catalyzes the reversible interconversion of maltose and trehalose by transglucosylation. Maltose is the preferred substrate. To a lesser extent, also displays amylase activity, catalyzing the endohydrolysis of (1->4)-alpha-D- glucosidic linkages in glycogen and maltooligosaccharides such as maltoheptaose, to produce maltose which then can be converted to trehalose. TreS plays a key role in the utilization of trehalose for the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P). Might also functio [...]
 
  
 0.728
treZ
Malto-oligosyltrehalose trehalohydrolase; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402.
 
  
 0.656
ABK72415.1
Glycoside hydrolase; Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose. Does not hydrolyze maltose, isomaltose, sucrose, cellobiose, p-nitrophenyl-alpha-D-glucopyranoside, and methyl- alpha-D-glucopyranoside. Is also inactive on alpha,beta-trehalose, beta,beta-trehalose, alpha,alpha-trehalose-6,6'-dibehenate, trehalulose, nigerose, and trehalose dimycolate.
  
   
 0.650
ABK69716.1
Conserved hypothetical protein.
  
    0.566
ABK71596.1
Conserved hypothetical protein.
  
    0.564
ABK75698.1
Amylo-alpha-1,6-glucosidase; Identified by match to protein family HMM PF06202.
 
  
 0.521
ABK74424.1
Identified by match to protein family HMM PF00128.
 
  
 0.516
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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