node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70555.1 | ABK73366.1 | MSMEG_3958 | MSMEG_3955 | Glyoxalase/bleomycin resistance protein/dioxygenase. | Conserved hypothetical protein. | 0.673 |
ABK70555.1 | ABK74231.1 | MSMEG_3958 | MSMEG_3956 | Glyoxalase/bleomycin resistance protein/dioxygenase. | Alkylhydroperoxidase AhpD. | 0.553 |
ABK70555.1 | ABK75212.1 | MSMEG_3958 | MSMEG_3959 | Glyoxalase/bleomycin resistance protein/dioxygenase. | Transcriptional regulator; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729. | 0.524 |
ABK70555.1 | ABK75333.1 | MSMEG_3958 | MSMEG_3957 | Glyoxalase/bleomycin resistance protein/dioxygenase. | Conserved 13e12 repeat family protein; Identified by match to protein family HMM PF01844; match to protein family HMM PF02720. | 0.522 |
ABK73366.1 | ABK70555.1 | MSMEG_3955 | MSMEG_3958 | Conserved hypothetical protein. | Glyoxalase/bleomycin resistance protein/dioxygenase. | 0.673 |
ABK73366.1 | ABK74231.1 | MSMEG_3955 | MSMEG_3956 | Conserved hypothetical protein. | Alkylhydroperoxidase AhpD. | 0.693 |
ABK73366.1 | ABK75333.1 | MSMEG_3955 | MSMEG_3957 | Conserved hypothetical protein. | Conserved 13e12 repeat family protein; Identified by match to protein family HMM PF01844; match to protein family HMM PF02720. | 0.734 |
ABK73669.1 | ABK74231.1 | MSMEG_4891 | MSMEG_3956 | Alkylhydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in det [...] | Alkylhydroperoxidase AhpD. | 0.575 |
ABK73669.1 | ahpD | MSMEG_4891 | MSMEG_4890 | Alkylhydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in det [...] | Alkylhydroperoxidase, AhpD family protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. | 0.998 |
ABK73669.1 | cysNC | MSMEG_4891 | MSMEG_4978 | Alkylhydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in det [...] | Sulfate adenylytransferase, large subunit/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.440 |
ABK73669.1 | katG | MSMEG_4891 | MSMEG_3461 | Alkylhydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in det [...] | Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. May play a role in the intracellular survival of mycobacteria. | 0.593 |
ABK73669.1 | katG-2 | MSMEG_4891 | MSMEG_3729 | Alkylhydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in det [...] | Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.516 |
ABK73669.1 | katG-3 | MSMEG_4891 | MSMEG_6384 | Alkylhydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in det [...] | Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. May play a role in the intracellular survival of mycobacteria. | 0.558 |
ABK74231.1 | ABK70555.1 | MSMEG_3956 | MSMEG_3958 | Alkylhydroperoxidase AhpD. | Glyoxalase/bleomycin resistance protein/dioxygenase. | 0.553 |
ABK74231.1 | ABK73366.1 | MSMEG_3956 | MSMEG_3955 | Alkylhydroperoxidase AhpD. | Conserved hypothetical protein. | 0.693 |
ABK74231.1 | ABK73669.1 | MSMEG_3956 | MSMEG_4891 | Alkylhydroperoxidase AhpD. | Alkylhydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in det [...] | 0.575 |
ABK74231.1 | ABK75212.1 | MSMEG_3956 | MSMEG_3959 | Alkylhydroperoxidase AhpD. | Transcriptional regulator; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729. | 0.402 |
ABK74231.1 | ABK75333.1 | MSMEG_3956 | MSMEG_3957 | Alkylhydroperoxidase AhpD. | Conserved 13e12 repeat family protein; Identified by match to protein family HMM PF01844; match to protein family HMM PF02720. | 0.776 |
ABK74231.1 | ahpD | MSMEG_3956 | MSMEG_4890 | Alkylhydroperoxidase AhpD. | Alkylhydroperoxidase, AhpD family protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. | 0.517 |
ABK74231.1 | cysNC | MSMEG_3956 | MSMEG_4978 | Alkylhydroperoxidase AhpD. | Sulfate adenylytransferase, large subunit/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.458 |