STRINGSTRING
ABK71921.1 ABK71921.1 sucA sucA ABK70730.1 ABK70730.1 ABK72864.1 ABK72864.1 sucB sucB ABK74408.1 ABK74408.1 gcvH gcvH ABK70172.1 ABK70172.1 prs prs gcvT gcvT ABK72436.1 ABK72436.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK71921.1Oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992. (495 aa)    
Predicted Functional Partners:
sucA
2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...]
  
 0.996
ABK70730.1
Transketolase, central region; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM PF02780.
  
 0.989
ABK72864.1
Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
 0.918
sucB
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM TIGR02927.
 0.908
ABK74408.1
Pyruvate dehydrogenase E1 component subunit beta; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780.
 
 0.903
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
  
 0.849
ABK70172.1
Pyruvate dehydrogenase E1 component, alpha subunit; Identified by match to protein family HMM PF00676.
 
 
 0.849
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.833
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.782
ABK72436.1
Conserved hypothetical protein.
  
 0.747
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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