ABK71395.1 protein (Mycolicibacterium smegmatis)

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ABK71395.1

Translation initiation inhibitor; Identified by match to protein family HMM PF01042. (142 aa)

Predicted Functional Partners:

ABK72122.1

0.681

ABK73573.1

0.671

murQ

0.586

murD

0.559

murE

0.559

rph

0.480

nnrD

0.463

ABK70501.1

0.437

ribD

0.410

Your Current Organism:

Mycolicibacterium smegmatis

NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK70501.1	ABK71395.1	MSMEG_6591	MSMEG_4061	Aminotransferase, class V family protein; Identified by match to protein family HMM PF00266.	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	0.437
ABK71395.1	ABK70501.1	MSMEG_4061	MSMEG_6591	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	Aminotransferase, class V family protein; Identified by match to protein family HMM PF00266.	0.437
ABK71395.1	ABK72122.1	MSMEG_4061	MSMEG_4062	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	glutamyl-tRNA(Gln) amidotransferase subunit A; Identified by match to protein family HMM PF01425; Belongs to the amidase family.	0.681
ABK71395.1	ABK73573.1	MSMEG_4061	MSMEG_6535	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	Translation elongation factor EF-G; Identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF03764; match to protein family HMM TIGR00231.	0.671
ABK71395.1	murD	MSMEG_4061	MSMEG_4229	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	0.559
ABK71395.1	murE	MSMEG_4061	MSMEG_4232	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.	0.559
ABK71395.1	murQ	MSMEG_4061	MSMEG_0193	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	Putative glucokinase regulator; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.	0.586
ABK71395.1	nnrD	MSMEG_4061	MSMEG_1573	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.463
ABK71395.1	ribD	MSMEG_4061	MSMEG_3067	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.410
ABK71395.1	rph	MSMEG_4061	MSMEG_4901	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.480
ABK72122.1	ABK71395.1	MSMEG_4062	MSMEG_4061	glutamyl-tRNA(Gln) amidotransferase subunit A; Identified by match to protein family HMM PF01425; Belongs to the amidase family.	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	0.681
ABK73573.1	ABK71395.1	MSMEG_6535	MSMEG_4061	Translation elongation factor EF-G; Identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF03764; match to protein family HMM TIGR00231.	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	0.671
murD	ABK71395.1	MSMEG_4229	MSMEG_4061	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	0.559
murD	murE	MSMEG_4229	MSMEG_4232	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.	0.999
murD	ribD	MSMEG_4229	MSMEG_3067	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.430
murE	ABK71395.1	MSMEG_4232	MSMEG_4061	UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	0.559
murE	murD	MSMEG_4232	MSMEG_4229	UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	0.999
murQ	ABK71395.1	MSMEG_0193	MSMEG_4061	Putative glucokinase regulator; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	0.586
nnrD	ABK71395.1	MSMEG_1573	MSMEG_4061	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	0.463
ribD	ABK71395.1	MSMEG_3067	MSMEG_4061	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	Translation initiation inhibitor; Identified by match to protein family HMM PF01042.	0.410