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pntB-2 pntB-2 pntA pntA ABK71348.1 ABK71348.1 pntA-2 pntA-2 ABK74118.1 ABK74118.1 sthA sthA nadE nadE ABK72576.1 ABK72576.1 nadD nadD nadK nadK sir2 sir2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pntB-2NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (479 aa)    
Predicted Functional Partners:
pntA
NAD(P) transhydrogenase, alpha subunit; Identified by similarity to SP:P07001; match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00561.
 0.999
ABK71348.1
Alanine dehydrogenase/pyridine nucleotide transhydrogenase; Identified by match to protein family HMM PF01262; match to protein family HMM PF05222.
 0.999
pntA-2
NAD(P) transhydrogenase, alpha subunit; Identified by similarity to SP:P07001; match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00561.
 0.999
ABK74118.1
PntAB protein.
 
 0.995
sthA
Soluble pyridine nucleotide transhydrogenase; Identified by similarity to SP:P27306; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992.
   
 
 0.956
nadE
Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 
 0.916
ABK72576.1
NAD(P) transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
  
  
 
0.909
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.909
nadK
Inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NADkinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
   
 
 0.908
sir2
NAD-dependent deacetylase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.
  
 
  0.905
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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