STRINGSTRING
ABK70362.1 ABK70362.1 rpoZ rpoZ ABK72041.1 ABK72041.1 metH metH ABK70869.1 ABK70869.1 ABK76059.1 ABK76059.1 ABK74527.1 ABK74527.1 ABK73491.1 ABK73491.1 prcA prcA prcB prcB ABK76099.1 ABK76099.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK70362.1Conserved hypothetical protein; Identified by match to protein family HMM PF01908. (292 aa)    
Predicted Functional Partners:
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
    0.669
ABK72041.1
Cytochrome aa3 controlling protein; Identified by match to protein family HMM PF02628.
  
    0.636
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.630
ABK70869.1
Conserved hypothetical protein.
  
   
 0.588
ABK76059.1
Conserved hypothetical protein; Belongs to the UPF0336 family.
  
    0.575
ABK74527.1
Conserved hypothetical protein; Belongs to the UPF0336 family.
  
    0.567
ABK73491.1
Conserved hypothetical protein; Belongs to the UPF0336 family.
  
    0.554
prcA
Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.smegmatis proteasome is able to cleave oligopeptides after hydrophobic residues, thus displaying chymotrypsin-like activity. In complex with the ATPase Mpa, degrades protein targets conjugated to a prokaryotic ubiquitin- like protein (Pup). Identified substrates of the M.smegmatis proteasome are the pupylated SodA and Ino1 proteins. The Pup- proteasome system (PPS) is essential for survival under starvation; PPS likely functions to recycle a [...]
 
 
 0.547
prcB
Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.smegmatis proteasome is able to cleave oligopeptides after hydrophobic residues, thus displaying chymotrypsin-like activity. In complex with the ATPase Mpa, degrades protein targets conjugated to a prokaryotic ubiquitin- like protein (Pup). Among the identified substrates of the M.smegmatis proteasome are the pupylated SodA and Ino1 proteins. The Pup-proteasome system (PPS) is essential for survival under starvation; PPS likely functions to r [...]
 
 
 0.545
ABK76099.1
Acetyltransferase; Identified by match to protein family HMM PF00583.
  
    0.510
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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