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ABK70694.1 ABK70694.1 uppS-2 uppS-2 ABK70725.1 ABK70725.1 ispH ispH ABK72053.1 ABK72053.1 fni fni ABK75453.1 ABK75453.1 uppS uppS ABK74949.1 ABK74949.1 dxs dxs ABK73353.1 ABK73353.1
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Predicted Interactions
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ABK70694.1Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. (362 aa)    
Predicted Functional Partners:
uppS-2
Undecaprenyl diphosphate synthase; Catalyzes the condensation of only one isopentenyl pyrophosphate (IPP) unit in the cis configuration to E-geranyl diphosphate (E-GPP) generating the 15 carbon product (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP). Z-FPP is the precursor of decaprenyl diphosphate, which has a central role in the biosynthesis of the mycobacterial cell wall.
 
 
 0.976
ABK70725.1
Phytoene synthase; Identified by match to protein family HMM PF00494.
  
 0.972
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
 
 0.952
ABK72053.1
Bifunctional short chain isoprenyl diphosphate synthase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
  
 
0.930
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
 0.916
ABK75453.1
Possible conserved integral membrane protein.
 
 
 0.847
uppS
Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) in the cis configuration with (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP) generating the 50 carbon product trans,polycis-decaprenyl diphosphate. When (2E,6E)-farnesyl diphosphate (E-FPP or EE-FPP) is used in vitro, both primary products decaprenyl diphosphate and heptaprenyl diphosphate are synthesized. It is probably due to the fact that M.smegmatis synthesizes both (2E,6E,10E)- geranylgeranyl diphosphate (EEE-GGPP) and (2E,6E,10Z)-geranylgeranyl diphosphate (EEZ-GGPP). Can als [...]
 
  
 0.809
ABK74949.1
Phytoene dehydrogenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01593; match to protein family HMM TIGR02734.
 
  
 0.804
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
 
  
 0.739
ABK73353.1
LppM protein.
 
  
 0.671
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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