STRINGSTRING
ABK74084.1 ABK74084.1 uvrB uvrB polA polA cinA cinA ABK71856.1 ABK71856.1 ABK73029.1 ABK73029.1 ABK74484.1 ABK74484.1 radA radA sun sun ABK74586.1 ABK74586.1 ABK76190.1 ABK76190.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK74084.1DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. (672 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
 
 
 0.951
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 
 0.943
cinA
Identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family.
  
  
 0.879
ABK71856.1
ATP-dependent DNA helicase; Identified by match to protein family HMM PF00570; match to protein family HMM PF00580.
 
  
 0.875
ABK73029.1
Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily.
 
  
 0.832
ABK74484.1
ATP-dependent DNA helicase; Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily.
 
  
 0.819
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function (By similarity). Also inhibits the diadenylate cyclase activity of DisA ; Belongs to the Rec [...]
 
  
 0.786
sun
Ribosomal RNA small subunit methyltransferase B; Identified by match to protein family HMM PF01029; match to protein family HMM PF01189; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
  
 0.783
ABK74586.1
Endonuclease VIII and dna n-glycosylase with an ap lyase activity; Identified by match to protein family HMM PF01149; match to protein family HMM PF06827; match to protein family HMM PF06831; Belongs to the FPG family.
  
  
 0.777
ABK76190.1
Conserved hypothetical protein.
 
    0.741
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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