STRINGSTRING
ABK70615.1 ABK70615.1 ABK70006.1 ABK70006.1 ABK70918.1 ABK70918.1 ABK71812.1 ABK71812.1 ABK74757.1 ABK74757.1 pheT pheT radA radA ABK75428.1 ABK75428.1 ABK69693.1 ABK69693.1 ABK73643.1 ABK73643.1 polA polA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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Experiments
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[Homology]
Score
ABK70615.1methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (187 aa)    
Predicted Functional Partners:
ABK70006.1
RNA polymerase sigma factor, sigma-70 family protein; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.
 
  
 0.963
ABK70918.1
Transcriptional regulator, Ada family protein/DNA-3-methyladenine glycosylase II; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029.
 
  
 0.942
ABK71812.1
Conserved hypothetical protein.
 
    0.855
ABK74757.1
Deoxyribodipyrimidine photo-lyase; Identified by match to protein family HMM PF00875; match to protein family HMM PF03441; Belongs to the DNA photolyase family.
  
  
 0.753
pheT
phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.677
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function (By similarity). Also inhibits the diadenylate cyclase activity of DisA ; Belongs to the Rec [...]
  
  
 0.539
ABK75428.1
Hypothetical protein; Identified by Glimmer2; putative.
       0.532
ABK69693.1
Cobyrinic Acid a,c-diamide synthase; Identified by match to protein family HMM PF01656.
 
    0.522
ABK73643.1
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.481
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 
 0.472
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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