STRINGSTRING
ABK72894.1 ABK72894.1 ABK70589.1 ABK70589.1 rpoA rpoA ABK70456.1 ABK70456.1 rpoB rpoB rpoZ rpoZ rpoC rpoC ABK74955.1 ABK74955.1 sigA sigA ABK71462.1 ABK71462.1 ABK74841.1 ABK74841.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK72894.1Ferric uptake regulation protein; Identified by match to protein family HMM PF01475; Belongs to the Fur family. (136 aa)    
Predicted Functional Partners:
ABK70589.1
Transcriptional regulator, ArsR family protein; Identified by match to protein family HMM PF01022.
  
  
 0.931
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.923
ABK70456.1
Iron-dependent repressor IdeR; Identified by match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023.
  
  
 0.873
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription.
  
 
 0.803
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 0.797
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   0.788
ABK74955.1
Sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.767
sigA
Sigma factor MysA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.765
ABK71462.1
ABC heavy metal transporter, inner membrane subunit; Identified by match to protein family HMM PF00950.
  
  
 0.730
ABK74841.1
Ferric uptake regulation protein; Identified by match to protein family HMM PF01475; Belongs to the Fur family.
  
   
 0.696
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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