STRINGSTRING
ABK74394.1 ABK74394.1 ftsH ftsH ABK74866.1 ABK74866.1 ABK72764.1 ABK72764.1 saeC saeC ABK74179.1 ABK74179.1 ABK70031.1 ABK70031.1 ctpE ctpE mpa mpa metH metH ABK74175.1 ABK74175.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK74394.1SpfH domain protein; Identified by match to protein family HMM PF01145. (268 aa)    
Predicted Functional Partners:
ftsH
Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.949
ABK74866.1
Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family.
  
 0.782
ABK72764.1
Spfh domain/band 7 family protein, putative; Identified by match to protein family HMM PF01145.
  
 
 0.757
saeC
Conserved hypothetical protein; May be involved in assembly of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Involved in DNA conjugation in recipient (MKD8) strain.
   
 0.751
ABK74179.1
Identified by match to protein family HMM PF01694.
  
 0.717
ABK70031.1
Identified by match to protein family HMM PF01694.
  
 0.713
ctpE
P-type ATPase - metal cation transport; P-type ATPase involved in specific uptake of calcium. Essential for growth and maintenance of cell surface integrity under Ca(2+)-deficient conditions.
 
 0.657
mpa
ATPase, AAA family protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 
 0.656
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 0.656
ABK74175.1
Cation-transporting ATPase Pma1; Identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494.
 
 0.650
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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