STRINGSTRING
octT octT ABK74624.1 ABK74624.1 ABK71654.1 ABK71654.1 rsfS rsfS nadD nadD lipB lipB ABK72111.1 ABK72111.1 ABK71455.1 ABK71455.1 ABK72817.1 ABK72817.1 ABK72142.1 ABK72142.1 ABK70363.1 ABK70363.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
octTConserved hypothetical protein; Sugar octanoyltransferase likely involved in the biosynthesis of mycobacterial methylglucose lipopolysaccharide (MGLP). Catalyzes the transfer of an octanoyl group from octanoyl-CoA to the C6 OH of the second glucose in diglucosylglycerate (DGG). DGG is the preferred acceptor, but to a lesser extent, GG (glucosylglycerate) can also be used as substrate. DGG and GG are the two earliest intermediates in MGLP biosynthesis; Belongs to the OctT acyltransferase family. (252 aa)    
Predicted Functional Partners:
ABK74624.1
Identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762.
  
  
 0.955
ABK71654.1
Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.
  
  
 0.899
rsfS
Conserved domain protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
    0.894
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
    0.894
lipB
Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
  
  
 0.875
ABK72111.1
Conserved hypothetical protein; Probable S-adenosylmethionine-dependent methyltransferase required for the 6-O-methylation of the polysaccharide backbone of 6-O- methylglucosyl lipopolysaccharides (MGLP). Belongs to the methyltransferase superfamily.
 
  
 0.854
ABK71455.1
Glycosyl hydrolase, family protein 57; Identified by match to protein family HMM PF03065; Belongs to the glycosyl hydrolase 57 family.
  
  
 0.826
ABK72817.1
Identified by match to protein family HMM PF00132.
 
  
 0.823
ABK72142.1
Identified by match to protein family HMM PF00132.
 
   
 0.820
ABK70363.1
Conserved hypothetical protein.
 
    0.783
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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