node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70025.1 | ABK72469.1 | MSMEG_4631 | MSMEG_4632 | Conserved hypothetical protein. | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. | 0.560 |
ABK70025.1 | ABK75475.1 | MSMEG_4631 | MSMEG_4633 | Conserved hypothetical protein. | Peptidase S9, prolyl oligopeptidase; Identified by match to protein family HMM PF00326; match to protein family HMM PF05448. | 0.709 |
ABK70025.1 | ABK75851.1 | MSMEG_4631 | MSMEG_4634 | Conserved hypothetical protein. | Hypothetical protein; Identified by Glimmer2; putative. | 0.459 |
ABK70025.1 | valS | MSMEG_4631 | MSMEG_4630 | Conserved hypothetical protein. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.576 |
ABK70529.1 | ABK70717.1 | MSMEG_6767 | MSMEG_4513 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | Polyketide synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.540 |
ABK70529.1 | ABK72469.1 | MSMEG_6767 | MSMEG_4632 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. | 0.632 |
ABK70529.1 | inhA | MSMEG_6767 | MSMEG_3151 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | [NADH] enoyl-[acyl-carrier-protein] reductase; Enoyl-ACP reductase of the type II fatty acid syntase (FAS- II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the double bond of 2-trans- enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway. Shows preference for long-chain fatty acyl thioester substrates (>C16), and can also use 2-trans-enoyl-CoAs as alternative substrates (By similarity). The mycobacterial FAS-II system utilizes th [...] | 0.732 |
ABK70529.1 | pks5 | MSMEG_6767 | MSMEG_4727 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | Mycocerosic acid synthase; Polyketide synthase involved in the biosynthesis of 2,4- dimethyl-2-eicosenoic acid, a lipid component of the lipooligosaccharides (LOS) which are not located at the bacterial surface but rather in deeper compartments of the cell envelope of M.smegmatis. | 0.903 |
ABK70717.1 | ABK70529.1 | MSMEG_4513 | MSMEG_6767 | Polyketide synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | 0.540 |
ABK70717.1 | ABK72469.1 | MSMEG_4513 | MSMEG_4632 | Polyketide synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. | 0.733 |
ABK70717.1 | pks5 | MSMEG_4513 | MSMEG_4727 | Polyketide synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Mycocerosic acid synthase; Polyketide synthase involved in the biosynthesis of 2,4- dimethyl-2-eicosenoic acid, a lipid component of the lipooligosaccharides (LOS) which are not located at the bacterial surface but rather in deeper compartments of the cell envelope of M.smegmatis. | 0.570 |
ABK72469.1 | ABK70025.1 | MSMEG_4632 | MSMEG_4631 | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. | Conserved hypothetical protein. | 0.560 |
ABK72469.1 | ABK70529.1 | MSMEG_4632 | MSMEG_6767 | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | 0.632 |
ABK72469.1 | ABK70717.1 | MSMEG_4632 | MSMEG_4513 | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. | Polyketide synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.733 |
ABK72469.1 | ABK73137.1 | MSMEG_4632 | MSMEG_4643 | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. | Resuscitation-promoting factor; Identified by match to protein family HMM PF06737. | 0.631 |
ABK72469.1 | ABK75475.1 | MSMEG_4632 | MSMEG_4633 | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. | Peptidase S9, prolyl oligopeptidase; Identified by match to protein family HMM PF00326; match to protein family HMM PF05448. | 0.893 |
ABK72469.1 | ABK75851.1 | MSMEG_4632 | MSMEG_4634 | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. | Hypothetical protein; Identified by Glimmer2; putative. | 0.696 |
ABK72469.1 | ethA | MSMEG_4632 | MSMEG_6440 | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. | Monooxygenase, flavin-binding family protein; Monooxygenase able to convert a wide range of ketones to the corresponding esters or lactones via a Baeyer-Villiger oxidation reaction. Can act on long-chain aliphatic ketones (2-hexanone to 2- dodecanone) and on aromatic ketones (phenylacetone and benzylacetone). Is also able to catalyze enantioselective sulfoxidation of methyl-p- tolylsulfide. In vivo, likely functions as a BVMO, but the exact nature of the physiological substrate(s) remains to be established. | 0.613 |
ABK72469.1 | inhA | MSMEG_4632 | MSMEG_3151 | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. | [NADH] enoyl-[acyl-carrier-protein] reductase; Enoyl-ACP reductase of the type II fatty acid syntase (FAS- II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the double bond of 2-trans- enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway. Shows preference for long-chain fatty acyl thioester substrates (>C16), and can also use 2-trans-enoyl-CoAs as alternative substrates (By similarity). The mycobacterial FAS-II system utilizes th [...] | 0.901 |
ABK72469.1 | pks5 | MSMEG_4632 | MSMEG_4727 | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. | Mycocerosic acid synthase; Polyketide synthase involved in the biosynthesis of 2,4- dimethyl-2-eicosenoic acid, a lipid component of the lipooligosaccharides (LOS) which are not located at the bacterial surface but rather in deeper compartments of the cell envelope of M.smegmatis. | 0.655 |