STRINGSTRING
nucS nucS ABK74593.1 ABK74593.1 dnaN dnaN ABK70640.1 ABK70640.1 ABK70918.1 ABK70918.1 ABK74795.1 ABK74795.1 whiB whiB ABK72472.1 ABK72472.1 rpoZ rpoZ whiB2 whiB2 ABK70869.1 ABK70869.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nucSConserved hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (224 aa)    
Predicted Functional Partners:
ABK74593.1
Conserved hypothetical protein.
 
  
 0.975
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.856
ABK70640.1
Conserved hypothetical protein.
  
  
 0.806
ABK70918.1
Transcriptional regulator, Ada family protein/DNA-3-methyladenine glycosylase II; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029.
       0.767
ABK74795.1
Transcriptional regulator, MerR family protein.
  
    0.765
whiB
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
    0.764
ABK72472.1
DNA polymerase III, delta subunit; Identified by match to protein family HMM PF06144.
 
  
 0.764
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  
 0.759
whiB2
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity); Belongs to the WhiB family.
  
    0.755
ABK70869.1
Conserved hypothetical protein.
  
     0.724
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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