STRINGSTRING
prmC prmC prfA prfA ABK69723.1 ABK69723.1 ychF ychF wecA wecA rpmE rpmE ABK71692.1 ABK71692.1 ABK71679.1 ABK71679.1 ABK69999.1 ABK69999.1 ispG ispG pth pth
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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prmCModification methylase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (281 aa)    
Predicted Functional Partners:
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
 
 
 0.998
ABK69723.1
Identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Belongs to the SUA5 family.
 
  
 0.977
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.854
wecA
Glycosyl trasferase; Involved in the biosynthesis of the disaccharide D-N- acetylglucosamine-L-rhamnose which plays an important role in the mycobacterial cell wall as a linker connecting arabinogalactan and peptidoglycan via a phosphodiester linkage. Catalyzes the transfer of the N-acetylglucosamine-1-phosphate (GlcNAc-1P) moiety from UDP-GlcNAc onto the carrier lipid decaprenyl phosphate (C50-P), yielding GlcNAc- pyrophosphoryl-decaprenyl (GlcNAc-PP-C50).
  
    0.847
rpmE
Ribosomal protein L31; Binds the 23S rRNA.
  
  
 0.838
ABK71692.1
O-antigen export system, ATP-binding protein; Identified by match to protein family HMM PF00005.
  
  
 0.824
ABK71679.1
Fatty acid desaturase; Identified by match to protein family HMM PF03405.
   
  
 0.791
ABK69999.1
Hypothetical protein; Identified by Glimmer2; putative.
  
 0.734
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
  
  
 0.709
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
 
  
 0.662
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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