STRINGSTRING
glgC glgC glgM glgM glgB glgB ABK72491.1 ABK72491.1 glgX glgX otsA otsA glgX-2 glgX-2 malQ malQ treZ treZ galU galU glgE glgE
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query proteins and first shell of interactors
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. (404 aa)    
Predicted Functional Partners:
glgM
Glycogen synthase; Involved in the biosynthesis of the maltose-1-phosphate (M1P) building block required for alpha-glucan production by the key enzyme GlgE. Catalyzes the formation of an alpha-1,4 linkage between glucose from ADP-glucose and glucose 1-phosphate (G1P) to yield maltose-1- phosphate (M1P).
 
 
 0.999
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
  
 0.997
ABK72491.1
Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094.
 
 
 0.996
glgX
Glycogen debranching enzyme GlgX; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02100; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.987
otsA
Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Involved in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1- phosphate (M1P), and probably in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to glucose-6-phosphate (Glc-6-P) to form trehalose-6-phosphate. ADP-Glc, CDP-Glc, GDP- Glc and TDP-Glc are also glucosyl donors, however, when the pyrimidine sugar nucleotides (CDP-Glc, TDP-Glc and UDP-Glc) are used as substrates, there is an absolute requirement [...]
  
 
 0.986
glgX-2
Glycogen debranching enzyme GlgX; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02100; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.985
malQ
4-alpha-glucanotransferase; Identified by match to protein family HMM PF02446; match to protein family HMM TIGR00217.
 
 
 0.983
treZ
Malto-oligosyltrehalose trehalohydrolase; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402.
 
  
 0.982
galU
UTP-glucose-1-phosphate uridylyltransferase; Identified by match to protein family HMM PF00483.
   
 
 0.980
glgE
Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
 
  
 0.976
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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