node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69794.1 | argD | MSMEG_5725 | MSMEG_3773 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | Acetylornithine aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01212; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.915 |
ABK69794.1 | dapA | MSMEG_5725 | MSMEG_2684 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.460 |
ABK69794.1 | dapD | MSMEG_5725 | MSMEG_5104 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.971 |
ABK69794.1 | dapE | MSMEG_5725 | MSMEG_5103 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. | 0.957 |
ABK69794.1 | dapF | MSMEG_5725 | MSMEG_2735 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.602 |
ABK69794.1 | lysA | MSMEG_5725 | MSMEG_4958 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.504 |
ABK72850.1 | dapA | MSMEG_5121 | MSMEG_2684 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.557 |
ABK72850.1 | dapB-3 | MSMEG_5121 | MSMEG_2664 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.798 |
ABK72850.1 | dapD | MSMEG_5121 | MSMEG_5104 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.917 |
ABK72850.1 | dapE | MSMEG_5121 | MSMEG_5103 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. | 0.955 |
ABK72850.1 | dapF | MSMEG_5121 | MSMEG_2735 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.898 |
ABK72850.1 | lysA | MSMEG_5121 | MSMEG_4958 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.867 |
ABK72850.1 | murB | MSMEG_5121 | MSMEG_0928 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.403 |
ABK72850.1 | murD | MSMEG_5121 | MSMEG_4229 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.480 |
argD | ABK69794.1 | MSMEG_3773 | MSMEG_5725 | Acetylornithine aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01212; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | 0.915 |
argD | dapA | MSMEG_3773 | MSMEG_2684 | Acetylornithine aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01212; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.520 |
argD | dapD | MSMEG_3773 | MSMEG_5104 | Acetylornithine aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01212; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.916 |
argD | dapE | MSMEG_3773 | MSMEG_5103 | Acetylornithine aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01212; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. | 0.914 |
argD | dapF | MSMEG_3773 | MSMEG_2735 | Acetylornithine aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01212; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.523 |
argD | lysA | MSMEG_3773 | MSMEG_4958 | Acetylornithine aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01212; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.507 |