STRINGSTRING
ABK69979.1 ABK69979.1 pruA pruA proC proC ABK73926.1 ABK73926.1 ctaD ctaD ABK71351.1 ABK71351.1 ABK74877.1 ABK74877.1 putP putP ald ald ABK70816.1 ABK70816.1 ABK72632.1 ABK72632.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK69979.1Proline dehydrogenase; Identified by match to protein family HMM PF01619. (317 aa)    
Predicted Functional Partners:
pruA
1-pyrroline-5-carboxylate dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236.
 0.999
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
 0.986
ABK73926.1
Conserved hypothetical protein.
 
  
 0.883
ctaD
Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
 
 0.729
ABK71351.1
Sodium:solute symporter; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.682
ABK74877.1
Integral membrane transport protein; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.679
putP
Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.679
ald
Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. May be required for the adaptation from aerobic growth to anaerobic dormancy. I could be involved in the maintenance of the NAD pool during the shift to an anaerobic dormant state in which oxygen as a terminal electron acceptor becomes limited.
  
  
 0.656
ABK70816.1
Identified by match to protein family HMM PF02554.
   
  
 0.582
ABK72632.1
AMP-dependent synthetase and ligase; Identified by match to protein family HMM PF00501.
 
  
 0.552
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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