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fumC fumC ABK72215.1 ABK72215.1 sdhA sdhA SdhA SdhA mqo mqo glcB glcB sdhB sdhB ABK73723.1 ABK73723.1 ABK69749.1 ABK69749.1 ABK71393.1 ABK71393.1 sdhC sdhC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (468 aa)    
Predicted Functional Partners:
ABK72215.1
Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.985
sdhA
Succinate dehydrogenase, flavoprotein subunit; Identified by similarity to SP:P31038; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01812; match to protein family HMM TIGR01816.
 0.980
SdhA
Succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM PF07992.
 0.976
mqo
Malate:quinone-oxidoreductase; Identified by match to protein family HMM PF01266; match to protein family HMM PF06039; match to protein family HMM TIGR01320.
  
 
 0.976
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.976
sdhB
Succinate dehydrogenase, iron-sulfur protein; Identified by similarity to SP:P51053; match to protein family HMM TIGR00384.
 
 0.968
ABK73723.1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF02910.
 0.966
ABK69749.1
NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.
 
 
 0.964
ABK71393.1
Succinate dehydrogenase; Identified by match to protein family HMM PF00111; match to protein family HMM TIGR00384.
  
 0.962
sdhC
Succinate dehydrogenase, cytochrome b556 subunit; Identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970.
  
 
 0.961
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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