node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK71627.1 | ABK74591.1 | MSMEG_0482 | MSMEG_0157 | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family. | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.635 |
ABK71627.1 | ABK75186.1 | MSMEG_0482 | MSMEG_5297 | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family. | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.646 |
ABK71627.1 | ilvC | MSMEG_0482 | MSMEG_2374 | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.996 |
ABK71627.1 | ilvN | MSMEG_0482 | MSMEG_2373 | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family. | Acetolactate synthase, small subunit; Identified by match to protein family HMM PF01842; match to protein family HMM TIGR00119; Belongs to the acetolactate synthase small subunit family. | 0.917 |
ABK71627.1 | leuA | MSMEG_0482 | MSMEG_6271 | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.963 |
ABK73913.1 | ABK74591.1 | MSMEG_5295 | MSMEG_0157 | Peroxisomal-coenzyme A synthetase; Identified by match to protein family HMM PF00501. | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.524 |
ABK73913.1 | ABK75186.1 | MSMEG_5295 | MSMEG_5297 | Peroxisomal-coenzyme A synthetase; Identified by match to protein family HMM PF00501. | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.834 |
ABK74591.1 | ABK71627.1 | MSMEG_0157 | MSMEG_0482 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family. | 0.635 |
ABK74591.1 | ABK73913.1 | MSMEG_0157 | MSMEG_5295 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Peroxisomal-coenzyme A synthetase; Identified by match to protein family HMM PF00501. | 0.524 |
ABK74591.1 | ABK75186.1 | MSMEG_0157 | MSMEG_5297 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.903 |
ABK74591.1 | frc | MSMEG_0157 | MSMEG_0158 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Formyl-coenzyme A transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily. | 0.980 |
ABK74591.1 | frc-2 | MSMEG_0157 | MSMEG_0168 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Formyl-coenzyme A transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily. | 0.686 |
ABK74591.1 | ilvC | MSMEG_0157 | MSMEG_2374 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.656 |
ABK74591.1 | ilvN | MSMEG_0157 | MSMEG_2373 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Acetolactate synthase, small subunit; Identified by match to protein family HMM PF01842; match to protein family HMM TIGR00119; Belongs to the acetolactate synthase small subunit family. | 0.844 |
ABK74591.1 | katA | MSMEG_0157 | MSMEG_3486 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Catalase KatA; Identified by similarity to SP:P26901; match to protein family HMM PF00199. | 0.636 |
ABK74591.1 | katA-2 | MSMEG_0157 | MSMEG_6232 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Catalase KatA; Identified by similarity to SP:P26901; match to protein family HMM PF00199. | 0.635 |
ABK74591.1 | leuA | MSMEG_0157 | MSMEG_6271 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.632 |
ABK75186.1 | ABK71627.1 | MSMEG_5297 | MSMEG_0482 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family. | 0.646 |
ABK75186.1 | ABK73913.1 | MSMEG_5297 | MSMEG_5295 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | Peroxisomal-coenzyme A synthetase; Identified by match to protein family HMM PF00501. | 0.834 |
ABK75186.1 | ABK74591.1 | MSMEG_5297 | MSMEG_0157 | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.903 |