STRINGSTRING
ABK73778.1 ABK73778.1 rbpA rbpA ABK74795.1 ABK74795.1 whiA whiA ABK73676.1 ABK73676.1 ABK72286.1 ABK72286.1 ABK72160.1 ABK72160.1 rpoZ rpoZ ABK72472.1 ABK72472.1 ABK70869.1 ABK70869.1 clgR clgR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
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Coexpression
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[Homology]
Score
ABK73778.1Conserved hypothetical protein. (99 aa)    
Predicted Functional Partners:
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), probably stimulating transcriptions from principal, but not alternative sigma factor promoters (By similarity). Partially restores transcription in the presence of rifampicin (Rif) in vitro; overexpression leads to an increase in the Rif tolerance in vivo, with smaller colonies. Seems to act by removing Rif from its binding site and preventing its further binding. No longer stimulates transcription in Rif-resistant RNA polymerase (with mutations in rpoB).
  
    0.777
ABK74795.1
Transcriptional regulator, MerR family protein.
  
    0.776
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
    0.772
ABK73676.1
Conserved hypothetical protein.
  
    0.766
ABK72286.1
ATPase involved in DNA repair; Identified by match to protein family HMM PF03993.
  
    0.760
ABK72160.1
Conserved hypothetical protein.
  
    0.760
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
    0.757
ABK72472.1
DNA polymerase III, delta subunit; Identified by match to protein family HMM PF06144.
  
    0.757
ABK70869.1
Conserved hypothetical protein.
  
    0.754
clgR
Transcriptional regulator, XRE family protein; Probably controls the response to vancomycin treatment; vancomycin induces expression of the clp regulon (clpP1, clpP2 and clpC1).
  
    0.754
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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