STRINGSTRING
recQ recQ ABK70942.1 ABK70942.1 recA recA ABK73907.1 ABK73907.1 deaD deaD topA topA ABK75618.1 ABK75618.1 recG recG polA polA ABK70223.1 ABK70223.1 ABK72176.1 ABK72176.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
recQATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00271. (381 aa)    
Predicted Functional Partners:
ABK70942.1
ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270.
    0.991
recA
Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...]
  
 0.947
ABK73907.1
ATP-dependent DNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614.
  
 
0.945
deaD
ATP-dependent rna helicase, dead/deah box family protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
 
0.942
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
  
 0.923
ABK75618.1
DNA repair exonuclease; Identified by match to protein family HMM PF00149.
  
 0.883
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
  
  
 0.865
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.861
ABK70223.1
DEAD/DEAH box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271.
 
  
 0.859
ABK72176.1
ATP-dependent RNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271.
 
 
 0.834
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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