node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70223.1 | recA | MSMEG_1757 | MSMEG_2723 | DEAD/DEAH box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...] | 0.739 |
ABK70223.1 | recG | MSMEG_1757 | MSMEG_2403 | DEAD/DEAH box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.460 |
ABK70223.1 | recQ | MSMEG_1757 | MSMEG_5397 | DEAD/DEAH box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00271. | 0.859 |
ABK70942.1 | ABK72176.1 | MSMEG_5399 | MSMEG_1540 | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270. | ATP-dependent RNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | 0.761 |
ABK70942.1 | ABK75618.1 | MSMEG_5399 | MSMEG_5004 | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270. | DNA repair exonuclease; Identified by match to protein family HMM PF00149. | 0.883 |
ABK70942.1 | deaD | MSMEG_5399 | MSMEG_5042 | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270. | ATP-dependent rna helicase, dead/deah box family protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | 0.679 |
ABK70942.1 | polA | MSMEG_5399 | MSMEG_3839 | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.864 |
ABK70942.1 | recA | MSMEG_5399 | MSMEG_2723 | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270. | Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...] | 0.897 |
ABK70942.1 | recG | MSMEG_5399 | MSMEG_2403 | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.440 |
ABK70942.1 | recQ | MSMEG_5399 | MSMEG_5397 | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270. | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00271. | 0.991 |
ABK70942.1 | topA | MSMEG_5399 | MSMEG_6157 | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...] | 0.908 |
ABK72176.1 | ABK70942.1 | MSMEG_1540 | MSMEG_5399 | ATP-dependent RNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270. | 0.761 |
ABK72176.1 | ABK73907.1 | MSMEG_1540 | MSMEG_5935 | ATP-dependent RNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | ATP-dependent DNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | 0.678 |
ABK72176.1 | polA | MSMEG_1540 | MSMEG_3839 | ATP-dependent RNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.480 |
ABK72176.1 | recQ | MSMEG_1540 | MSMEG_5397 | ATP-dependent RNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00271. | 0.834 |
ABK72176.1 | topA | MSMEG_1540 | MSMEG_6157 | ATP-dependent RNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...] | 0.469 |
ABK73907.1 | ABK72176.1 | MSMEG_5935 | MSMEG_1540 | ATP-dependent DNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | ATP-dependent RNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | 0.678 |
ABK73907.1 | ABK75618.1 | MSMEG_5935 | MSMEG_5004 | ATP-dependent DNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | DNA repair exonuclease; Identified by match to protein family HMM PF00149. | 0.883 |
ABK73907.1 | deaD | MSMEG_5935 | MSMEG_5042 | ATP-dependent DNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | ATP-dependent rna helicase, dead/deah box family protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | 0.936 |
ABK73907.1 | polA | MSMEG_5935 | MSMEG_3839 | ATP-dependent DNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.864 |