STRINGSTRING
ABK70044.1 ABK70044.1 ABK71494.1 ABK71494.1 prs prs ABK70103.1 ABK70103.1 ABK75254.1 ABK75254.1 arsC arsC rplY rplY glmU glmU ABK72199.1 ABK72199.1 ABK70195.1 ABK70195.1 ABK70370.1 ABK70370.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK70044.1Retinol dehydrogenase 13; Identified by match to protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (290 aa)    
Predicted Functional Partners:
ABK71494.1
LpqT protein.
  
    0.851
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.745
ABK70103.1
Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801.
  
 0.742
ABK75254.1
Putative oxidoreductase; Identified by match to protein family HMM PF01243.
 
   0.711
arsC
Arsenate reductase; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014; Belongs to the ArsC family.
  
  
 0.694
rplY
Ribosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
  
  
 0.534
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
  
  
 0.528
ABK72199.1
Two-component sensor histidine kinase; Identified by match to protein family HMM PF00027; match to protein family HMM PF02518.
  
 0.526
ABK70195.1
Secreted protein.
  
 
 0.514
ABK70370.1
Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes.
  
 0.514
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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