node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69574.1 | ABK72391.1 | MSMEG_5670 | MSMEG_5668 | Efflux membrane protein; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily. | Putative transcriptional regulator; Identified by match to protein family HMM PF01047. | 0.834 |
ABK69574.1 | ABK76010.1 | MSMEG_5670 | MSMEG_5671 | Efflux membrane protein; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily. | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | 0.583 |
ABK71054.1 | ABK76010.1 | MSMEG_2188 | MSMEG_5671 | Integral membrane protein; Identified by match to protein family HMM PF00892. | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | 0.604 |
ABK72391.1 | ABK69574.1 | MSMEG_5668 | MSMEG_5670 | Putative transcriptional regulator; Identified by match to protein family HMM PF01047. | Efflux membrane protein; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily. | 0.834 |
ABK72391.1 | ABK76010.1 | MSMEG_5668 | MSMEG_5671 | Putative transcriptional regulator; Identified by match to protein family HMM PF01047. | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | 0.605 |
ABK75506.1 | ABK76010.1 | MSMEG_6073 | MSMEG_5671 | RNA methyltransferase, TrmH family protein, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | 0.410 |
ABK75506.1 | cysS-2 | MSMEG_6073 | MSMEG_6074 | RNA methyltransferase, TrmH family protein, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | cysteinyl-tRNA synthetase; Identified by match to protein family HMM PF01406; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.975 |
ABK76010.1 | ABK69574.1 | MSMEG_5671 | MSMEG_5670 | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | Efflux membrane protein; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily. | 0.583 |
ABK76010.1 | ABK71054.1 | MSMEG_5671 | MSMEG_2188 | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | Integral membrane protein; Identified by match to protein family HMM PF00892. | 0.604 |
ABK76010.1 | ABK72391.1 | MSMEG_5671 | MSMEG_5668 | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | Putative transcriptional regulator; Identified by match to protein family HMM PF01047. | 0.605 |
ABK76010.1 | ABK75506.1 | MSMEG_5671 | MSMEG_6073 | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | RNA methyltransferase, TrmH family protein, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.410 |
ABK76010.1 | cysS-2 | MSMEG_5671 | MSMEG_6074 | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | cysteinyl-tRNA synthetase; Identified by match to protein family HMM PF01406; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.630 |
ABK76010.1 | gltX | MSMEG_5671 | MSMEG_2383 | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.562 |
ABK76010.1 | gltX-2 | MSMEG_5671 | MSMEG_6306 | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | glutamyl-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | 0.622 |
ABK76010.1 | lysS | MSMEG_5671 | MSMEG_6094 | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | lysyl-tRNA synthetase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.784 |
ABK76010.1 | lysX | MSMEG_5671 | MSMEG_3796 | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | lysyl-tRNA synthetase; Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine res [...] | 0.673 |
ABK76010.1 | proS | MSMEG_5671 | MSMEG_2621 | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.780 |
cysS-2 | ABK75506.1 | MSMEG_6074 | MSMEG_6073 | cysteinyl-tRNA synthetase; Identified by match to protein family HMM PF01406; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family. | RNA methyltransferase, TrmH family protein, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.975 |
cysS-2 | ABK76010.1 | MSMEG_6074 | MSMEG_5671 | cysteinyl-tRNA synthetase; Identified by match to protein family HMM PF01406; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family. | YbaK/prolyl-tRNA synthetase associated region; Identified by match to protein family HMM PF04073. | 0.630 |
cysS-2 | gltX | MSMEG_6074 | MSMEG_2383 | cysteinyl-tRNA synthetase; Identified by match to protein family HMM PF01406; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.827 |