STRINGSTRING
ABK74465.1 ABK74465.1 ABK71805.1 ABK71805.1 ABK74484.1 ABK74484.1 ABK74343.1 ABK74343.1 ABK74424.1 ABK74424.1 glgE glgE treS treS ABK70205.1 ABK70205.1 ABK70307.1 ABK70307.1 ABK71136.1 ABK71136.1 ABK75740.1 ABK75740.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK74465.1Amino acid permease-associated region; Identified by match to protein family HMM PF00324. (474 aa)    
Predicted Functional Partners:
ABK71805.1
Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440.
 
    0.799
ABK74484.1
ATP-dependent DNA helicase; Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily.
  
 
 0.792
ABK74343.1
Alpha-amylase 3; Identified by match to protein family HMM PF00128.
  
 0.662
ABK74424.1
Identified by match to protein family HMM PF00128.
  
 0.660
glgE
Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
  
 0.659
treS
Trehalose synthase; Catalyzes the reversible interconversion of maltose and trehalose by transglucosylation. Maltose is the preferred substrate. To a lesser extent, also displays amylase activity, catalyzing the endohydrolysis of (1->4)-alpha-D- glucosidic linkages in glycogen and maltooligosaccharides such as maltoheptaose, to produce maltose which then can be converted to trehalose. TreS plays a key role in the utilization of trehalose for the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P). Might also functio [...]
  
 0.659
ABK70205.1
Amino acid permease, putative; Identified by match to protein family HMM PF00324.
  
     0.632
ABK70307.1
Putative esterase superfamily protein; Identified by match to protein family HMM PF00756.
  
    0.569
ABK71136.1
Amino acid permease family protein, putative; Identified by match to protein family HMM PF00324.
  
    0.536
ABK75740.1
Amino acid permease-associated region; Identified by match to protein family HMM PF00324.
  
     0.487
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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