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ABK71916.1 ABK71916.1 fgd fgd ABK69597.1 ABK69597.1 ABK75580.1 ABK75580.1 cofD cofD fbiB fbiB FbiC FbiC ABK73917.1 ABK73917.1 ABK72884.1 ABK72884.1 ABK75254.1 ABK75254.1 ABK73563.1 ABK73563.1
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
ABK71916.1Conserved hypothetical protein; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. (159 aa)    
Predicted Functional Partners:
fgd
F420-dependent glucose-6-phosphate dehydrogenase; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria. Cannot use NAD, NADP, FAD or FMN instead of coenzyme F420 as an electron acceptor. Exhibits nearly no activity with D-mannose-6- phosphate or D-fructose-6-phosphate as substrate. Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
  
   
 0.987
ABK69597.1
Conserved hypothetical protein.
  
  
 0.979
ABK75580.1
acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.957
cofD
Lppg:fo 2-phospho-l-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.930
fbiB
F420-0:gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. Is able to add up to six glutamates to F420-0, producing F420-3 as the major product with lesser amount of F420-4,5,6, consistent with it producing the polyglutamated F420 compounds present in Mycobacterium smegmatis. In the N-terminal section; belong [...]
 
  
 0.911
FbiC
FO synthase; Identified by match to protein family HMM PF04055; match to protein family HMM TIGR00423.
 
   
 0.876
ABK73917.1
Pyridoxamine 5'-phosphate oxidase family protein; Identified by match to protein family HMM PF01243.
 
  
 0.842
ABK72884.1
Pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Identified by match to protein family HMM PF01243.
 
  
 0.831
ABK75254.1
Putative oxidoreductase; Identified by match to protein family HMM PF01243.
  
  
 0.828
ABK73563.1
Putative acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771.
  
   0.803
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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