STRINGSTRING
ABK71630.1 ABK71630.1 ABK70576.1 ABK70576.1 ABK76042.1 ABK76042.1 ABK73938.1 ABK73938.1 ruvC ruvC ABK72418.1 ABK72418.1 ABK75381.1 ABK75381.1 ABK75396.1 ABK75396.1 phd phd thiC thiC ABK74432.1 ABK74432.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK71630.1Conserved hypothetical protein. (438 aa)    
Predicted Functional Partners:
ABK70576.1
Isochorismatase hydrolase; Identified by match to protein family HMM PF00857.
      
 0.733
ABK76042.1
Isochorismatase hydrolase; Identified by match to protein family HMM PF00857.
      
 0.733
ABK73938.1
Isochorismatase hydrolase; Identified by match to protein family HMM PF00857.
      
 0.733
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
  
 0.663
ABK72418.1
Conserved hypothetical protein; Identified by match to protein family HMM PF02720.
  
  
 0.624
ABK75381.1
Conserved hypothetical protein; Identified by match to protein family HMM PF02720.
  
  
 0.623
ABK75396.1
HNH endonuclease; Identified by match to protein family HMM PF01844; match to protein family HMM PF02720.
  
  
 0.616
phd
Hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the bacteriostatic effect of cognate toxin Doc. In M.smegmatis 3 TA systems (VapB-VapC, MazE-MazF and Phd-Doc) may be involved in monitoring the nutritional supply and physiological state of the cell, linking catabolic with anabolic reactions.
   
  
 0.586
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
     
 0.565
ABK74432.1
HNH endonuclease; Identified by match to protein family HMM PF01844; match to protein family HMM PF02720.
  
  
 0.562
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.