node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69990.1 | folK | MSMEG_4047 | MSMEG_6101 | Dihydropteroate synthase; Identified by match to protein family HMM PF00753. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. | 0.901 |
ABK69990.1 | folP | MSMEG_4047 | MSMEG_5085 | Dihydropteroate synthase; Identified by match to protein family HMM PF00753. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.911 |
ABK69990.1 | folP-2 | MSMEG_4047 | MSMEG_6103 | Dihydropteroate synthase; Identified by match to protein family HMM PF00753. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.912 |
ABK75441.1 | folB | MSMEG_6100 | MSMEG_6102 | Conserved hypothetical protein. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.903 |
ABK75441.1 | folE | MSMEG_6100 | MSMEG_6104 | Conserved hypothetical protein. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.903 |
ABK75441.1 | folK | MSMEG_6100 | MSMEG_6101 | Conserved hypothetical protein. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. | 0.897 |
ABK75441.1 | folP-2 | MSMEG_6100 | MSMEG_6103 | Conserved hypothetical protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.896 |
ABK75441.1 | ftsH | MSMEG_6100 | MSMEG_6105 | Conserved hypothetical protein. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.794 |
ABK75441.1 | panC | MSMEG_6100 | MSMEG_6097 | Conserved hypothetical protein. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.522 |
folB | ABK75441.1 | MSMEG_6102 | MSMEG_6100 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Conserved hypothetical protein. | 0.903 |
folB | folE | MSMEG_6102 | MSMEG_6104 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.998 |
folB | folK | MSMEG_6102 | MSMEG_6101 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. | 0.999 |
folB | folP | MSMEG_6102 | MSMEG_5085 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.992 |
folB | folP-2 | MSMEG_6102 | MSMEG_6103 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
folB | ftsH | MSMEG_6102 | MSMEG_6105 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.927 |
folB | panC | MSMEG_6102 | MSMEG_6097 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.579 |
folB | ribBA | MSMEG_6102 | MSMEG_3072 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.644 |
folB | ribD | MSMEG_6102 | MSMEG_3067 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.695 |
folE | ABK75441.1 | MSMEG_6104 | MSMEG_6100 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Conserved hypothetical protein. | 0.903 |
folE | folB | MSMEG_6104 | MSMEG_6102 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.998 |