node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK71738.1 | ABK72550.1 | MSMEG_1621 | MSMEG_1701 | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.933 |
ABK71738.1 | apt | MSMEG_1621 | MSMEG_2964 | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.961 |
ABK71738.1 | hpt | MSMEG_1621 | MSMEG_6110 | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.934 |
ABK72550.1 | ABK71738.1 | MSMEG_1701 | MSMEG_1621 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156. | 0.933 |
ABK72550.1 | ABK74721.1 | MSMEG_1701 | MSMEG_3634 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | 0.423 |
ABK72550.1 | apt | MSMEG_1701 | MSMEG_2964 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.972 |
ABK72550.1 | guaA | MSMEG_1701 | MSMEG_1610 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.633 |
ABK72550.1 | guaB | MSMEG_1701 | MSMEG_1602 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.412 |
ABK72550.1 | hpt | MSMEG_1701 | MSMEG_6110 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.955 |
ABK74721.1 | ABK72550.1 | MSMEG_3634 | MSMEG_1701 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.423 |
ABK74721.1 | apt | MSMEG_3634 | MSMEG_2964 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.418 |
ABK74721.1 | gmk | MSMEG_3634 | MSMEG_3051 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.609 |
ABK74721.1 | guaA | MSMEG_3634 | MSMEG_1610 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.998 |
ABK74721.1 | guaB | MSMEG_3634 | MSMEG_1602 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.951 |
ABK74721.1 | hpt | MSMEG_3634 | MSMEG_6110 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.931 |
ABK74721.1 | purA | MSMEG_3634 | MSMEG_0759 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.983 |
ABK74721.1 | purH | MSMEG_3634 | MSMEG_5515 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Bifunctional purine biosynthesis protein PurH; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. | 0.951 |
apt | ABK71738.1 | MSMEG_2964 | MSMEG_1621 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156. | 0.961 |
apt | ABK72550.1 | MSMEG_2964 | MSMEG_1701 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.972 |
apt | ABK74721.1 | MSMEG_2964 | MSMEG_3634 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | 0.418 |