node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69672.1 | panB | MSMEG_2919 | MSMEG_4298 | 2-dehydropantoate 2-reductase; Identified by match to protein family HMM PF02558. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.917 |
ABK69672.1 | panC | MSMEG_2919 | MSMEG_6097 | 2-dehydropantoate 2-reductase; Identified by match to protein family HMM PF02558. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.919 |
ABK69672.1 | panE | MSMEG_2919 | MSMEG_0153 | 2-dehydropantoate 2-reductase; Identified by match to protein family HMM PF02558. | 2-dehydropantoate 2-reductase; Identified by match to protein family HMM PF02558; match to protein family HMM TIGR00745. | 0.950 |
ABK69672.1 | panE-2 | MSMEG_2919 | MSMEG_6374 | 2-dehydropantoate 2-reductase; Identified by match to protein family HMM PF02558. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.924 |
ABK74059.1 | ABK74654.1 | MSMEG_6375 | MSMEG_6373 | Transporter, major facilitator family protein; Identified by match to protein family HMM PF07690. | Conserved hypothetical protein; Identified by match to protein family HMM PF05853. | 0.773 |
ABK74059.1 | ABK75072.1 | MSMEG_6375 | MSMEG_6376 | Transporter, major facilitator family protein; Identified by match to protein family HMM PF07690. | Transcriptional regulator LacI family protein; Identified by match to protein family HMM PF00356; match to protein family HMM PF00532. | 0.612 |
ABK74059.1 | panE-2 | MSMEG_6375 | MSMEG_6374 | Transporter, major facilitator family protein; Identified by match to protein family HMM PF07690. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.785 |
ABK74654.1 | ABK74059.1 | MSMEG_6373 | MSMEG_6375 | Conserved hypothetical protein; Identified by match to protein family HMM PF05853. | Transporter, major facilitator family protein; Identified by match to protein family HMM PF07690. | 0.773 |
ABK74654.1 | ABK75072.1 | MSMEG_6373 | MSMEG_6376 | Conserved hypothetical protein; Identified by match to protein family HMM PF05853. | Transcriptional regulator LacI family protein; Identified by match to protein family HMM PF00356; match to protein family HMM PF00532. | 0.585 |
ABK74654.1 | panE-2 | MSMEG_6373 | MSMEG_6374 | Conserved hypothetical protein; Identified by match to protein family HMM PF05853. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.812 |
ABK75072.1 | ABK74059.1 | MSMEG_6376 | MSMEG_6375 | Transcriptional regulator LacI family protein; Identified by match to protein family HMM PF00356; match to protein family HMM PF00532. | Transporter, major facilitator family protein; Identified by match to protein family HMM PF07690. | 0.612 |
ABK75072.1 | ABK74654.1 | MSMEG_6376 | MSMEG_6373 | Transcriptional regulator LacI family protein; Identified by match to protein family HMM PF00356; match to protein family HMM PF00532. | Conserved hypothetical protein; Identified by match to protein family HMM PF05853. | 0.585 |
ABK75072.1 | panE-2 | MSMEG_6376 | MSMEG_6374 | Transcriptional regulator LacI family protein; Identified by match to protein family HMM PF00356; match to protein family HMM PF00532. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.590 |
coaBC | coaD | MSMEG_3054 | MSMEG_2414 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.994 |
coaBC | panB | MSMEG_3054 | MSMEG_4298 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.787 |
coaBC | panC | MSMEG_3054 | MSMEG_6097 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.955 |
coaBC | panD | MSMEG_3054 | MSMEG_0021 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.476 |
coaBC | panE | MSMEG_3054 | MSMEG_0153 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 2-dehydropantoate 2-reductase; Identified by match to protein family HMM PF02558; match to protein family HMM TIGR00745. | 0.672 |
coaBC | panE-2 | MSMEG_3054 | MSMEG_6374 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.852 |
coaD | coaBC | MSMEG_2414 | MSMEG_3054 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.994 |